node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D778_00065 | D778_00067 | D778_00065 | D778_00067 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | 0.931 |
D778_00065 | D778_02240 | D778_00065 | D778_02240 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.736 |
D778_00065 | D778_02408 | D778_00065 | D778_02408 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.980 |
D778_00065 | fabZ | D778_00065 | D778_00068 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.990 |
D778_00065 | lpxD | D778_00065 | D778_00069 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.957 |
D778_00065 | lpxK | D778_00065 | D778_00767 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.793 |
D778_00067 | D778_00065 | D778_00067 | D778_00065 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 0.931 |
D778_00067 | D778_00093 | D778_00067 | D778_00093 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | UDP-N-acetylglucosamine 4,6-dehydratase. | 0.903 |
D778_00067 | D778_01241 | D778_00067 | D778_01241 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | 0.934 |
D778_00067 | D778_01868 | D778_00067 | D778_01868 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.906 |
D778_00067 | D778_02240 | D778_00067 | D778_02240 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.833 |
D778_00067 | D778_02408 | D778_00067 | D778_02408 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.962 |
D778_00067 | D778_02568 | D778_00067 | D778_02568 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.907 |
D778_00067 | fabZ | D778_00067 | D778_00068 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.999 |
D778_00067 | lpxD | D778_00067 | D778_00069 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.984 |
D778_00067 | lpxK | D778_00067 | D778_00767 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.836 |
D778_00093 | D778_00067 | D778_00093 | D778_00067 | UDP-N-acetylglucosamine 4,6-dehydratase. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase. | 0.903 |
D778_00093 | D778_01241 | D778_00093 | D778_01241 | UDP-N-acetylglucosamine 4,6-dehydratase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | 0.904 |
D778_00093 | D778_01868 | D778_00093 | D778_01868 | UDP-N-acetylglucosamine 4,6-dehydratase. | UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.932 |
D778_00093 | D778_02568 | D778_00093 | D778_02568 | UDP-N-acetylglucosamine 4,6-dehydratase. | UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.917 |