STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D778_02520Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (427 aa)    
Predicted Functional Partners:
D778_00805
Branched-chain alpha-keto acid dehydrogenase.
 0.999
D778_00990
Branched-chain alpha-keto acid dehydrogenase.
 
 0.999
D778_01020
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit.
 0.999
D778_02091
2-oxoglutarate dehydrogenase E1 component.
 0.998
D778_01349
Dihydrolipoamide dehydrogenase.
 0.991
lpdA
Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.
 0.991
D778_02255
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.976
D778_00269
Pyruvate dehydrogenase E1 component alpha subunit.
 0.922
sucC
Succinyl-CoA ligase [ADP-forming] beta chain.
 
 0.922
sucD
Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.910
Your Current Organism:
Xanthomarina gelatinilytica
NCBI taxonomy Id: 1137281
Other names: Formosa sp. AK20, JCM 18821, MTCC 11705, X. gelatinilytica, Xanthomarina gelatinilytica Vaidya et al. 2015, strain AK20
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