STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQW22187.1Peptidase M24 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)    
Predicted Functional Partners:
AQW22186.1
Catabolite control protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.833
AQW22110.1
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
 
 0.679
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.651
AQW21943.1
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.588
AQW21518.1
Xaa-Pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
  
   
 0.546
AQW21898.1
Dipeptidase PepV; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.504
AQW21550.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.499
AQW22130.1
histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.478
AQW22049.1
GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.467
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
   
 
 0.463
Your Current Organism:
Lactobacillus curieae
NCBI taxonomy Id: 1138822
Other names: CCTCC M 2011381, JCM 18524, L. curieae, Lactobacillus curieae Lei et al. 2013, Lactobacillus sp. CCTCC M 2011381, strain S1L19
Server load: low (24%) [HD]