STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2DQQ7HotDog domain-containing protein. (166 aa)    
Predicted Functional Partners:
A0A1Y2E3B4
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
   
 0.634
A0A1Y2DRP5
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
  0.584
A0A1Y2E1M3
HotDog domain-containing protein.
    
 0.562
A0A1Y2EC94
HotDog domain-containing protein.
    
 0.562
A0A1Y2EAI4
Metallo-beta-lactamase family protein.
  
 
  0.493
A0A1Y2EIU6
2Fe-2S ferredoxin-type domain-containing protein.
  
 
  0.493
A0A1Y2DS40
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
 
      0.486
A0A1Y2EE03
Coronin; Belongs to the WD repeat coronin family.
    
 0.470
A0A1Y2EEG2
Cell division protein anillin-domain-containing protein.
    
 0.470
A0A1Y2DQY8
HotDog domain-containing protein.
     
 0.459
Your Current Organism:
Pseudomassariella vexata
NCBI taxonomy Id: 1141098
Other names: CBS 129021, Didymella vexata, Didymosphaeria vexata, Leiosphaerella vexata, P. vexata, WU 31333
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