A0A1Y2DSQ5 protein (Pseudomassariella vexata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

A0A1Y2DSQ5

Uncharacterized protein. (271 aa)

Predicted Functional Partners:

A0A1Y2EA53

0.777

A0A1Y2D831

0.761

A0A1Y2EJP1

0.754

A0A1Y2DLD7

0.656

A0A1Y2DWK9

0.655

A0A1Y2DS24

0.631

A0A1Y2DJY2

0.618

A0A1Y2DSB9

0.608

A0A1Y2E3V7

0.603

A0A1Y2DKS8

0.593

Your Current Organism:

Pseudomassariella vexata

NCBI taxonomy Id: 1141098
Other names: CBS 129021, Didymella vexata, Didymosphaeria vexata, Leiosphaerella vexata, P. vexata, WU 31333

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1Y2D831	A0A1Y2DLD7	P-loop containing nucleoside triphosphate hydrolase protein.	Ribosome biogenesis protein.	0.767
A0A1Y2D831	A0A1Y2DS24	P-loop containing nucleoside triphosphate hydrolase protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.967
A0A1Y2D831	A0A1Y2DSQ5	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein.	0.761
A0A1Y2D831	A0A1Y2DWK9	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein.	0.958
A0A1Y2D831	A0A1Y2EA53	P-loop containing nucleoside triphosphate hydrolase protein.	Pre-rRNA processing nucleolar protein-like protein Sik1.	0.963
A0A1Y2D831	A0A1Y2EJP1	P-loop containing nucleoside triphosphate hydrolase protein.	Fibrillarin-domain-containing protein.	0.968
A0A1Y2DJY2	A0A1Y2DSQ5	Fungal-specific transcription factor domain-domain-containing protein.	Uncharacterized protein.	0.618
A0A1Y2DKS8	A0A1Y2DLD7	RRM domain-containing protein.	Ribosome biogenesis protein.	0.735
A0A1Y2DKS8	A0A1Y2DS24	RRM domain-containing protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.436
A0A1Y2DKS8	A0A1Y2DSQ5	RRM domain-containing protein.	Uncharacterized protein.	0.593
A0A1Y2DKS8	A0A1Y2DWK9	RRM domain-containing protein.	Uncharacterized protein.	0.535
A0A1Y2DKS8	A0A1Y2E3V7	RRM domain-containing protein.	G-patch domain-containing protein.	0.673
A0A1Y2DLD7	A0A1Y2D831	Ribosome biogenesis protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.767
A0A1Y2DLD7	A0A1Y2DKS8	Ribosome biogenesis protein.	RRM domain-containing protein.	0.735
A0A1Y2DLD7	A0A1Y2DS24	Ribosome biogenesis protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.938
A0A1Y2DLD7	A0A1Y2DSQ5	Ribosome biogenesis protein.	Uncharacterized protein.	0.656
A0A1Y2DLD7	A0A1Y2DWK9	Ribosome biogenesis protein.	Uncharacterized protein.	0.894
A0A1Y2DLD7	A0A1Y2E3V7	Ribosome biogenesis protein.	G-patch domain-containing protein.	0.700
A0A1Y2DLD7	A0A1Y2EA53	Ribosome biogenesis protein.	Pre-rRNA processing nucleolar protein-like protein Sik1.	0.999
A0A1Y2DLD7	A0A1Y2EJP1	Ribosome biogenesis protein.	Fibrillarin-domain-containing protein.	0.999

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Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.934

expected number of edges:

10

PPI enrichment p-value:

5.09e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 105

1.33

2.33

3.59e-12

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 53

1.63

3.85

1.93e-15

GO:0019843

rRNA binding

6 of 41

1.48

1.89

4.28e-06

GO:0003723

RNA binding

7 of 100

1.16

1.28

1.59e-05

GO:0000049

tRNA binding

3 of 23

1.43

0.77

0.0220

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 56

1.61

3.8

6.09e-16

GO:0015935

Small ribosomal subunit

4 of 7

2.07

2.79

1.56e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:140

Ribosome

11 of 57

1.6

3.67

3.73e-15

CL:148

Structural constituent of ribosome

7 of 27

1.73

3.24

9.17e-10

CL:184

Mixed, incl. Small ribosomal subunit, and Ribosomal protein S13-like, H2TH

4 of 7

2.07

2.68

2.83e-06

CL:216

Ribosome

4 of 11

1.87

2.27

1.09e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

laca03010

Ribosome

11 of 53

1.63

3.94

3.53e-16

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

10 of 44

1.67

3.83

5.43e-14

GOCC:0015935

Small ribosomal subunit

6 of 13

1.98

3.69

2.69e-09

GOCC:0022627

Cytosolic small ribosomal subunit

5 of 11

1.97

3.15

9.09e-08

GOCC:0043229

Intracellular organelle

11 of 252

0.95

1.16

2.16e-09

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

11 of 55

1.61

3.82

9.29e-16

KW-0699

rRNA-binding

6 of 38

1.51

2.09

9.41e-07

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