node1 | node2 | node1 annotation | node2 annotation | score |
A0A1Y2D5M7 | A0A1Y2D869 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Phosphoribosyltransferase-like protein. | 0.883 |
A0A1Y2D5M7 | A0A1Y2DFE4 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Glutamine amidotransferase type-1 domain-containing protein. | 0.826 |
A0A1Y2D5M7 | A0A1Y2DIP4 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Glutamate 5-kinase. | 0.448 |
A0A1Y2D5M7 | A0A1Y2DUL4 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Uncharacterized protein. | 0.986 |
A0A1Y2D5M7 | A0A1Y2E1V4 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | FAD-binding PCMH-type domain-containing protein. | 0.879 |
A0A1Y2D5M7 | A0A1Y2EDY1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.826 |
A0A1Y2D5M7 | A0A1Y2EKG4 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.925 |
A0A1Y2D869 | A0A1Y2D5M7 | Phosphoribosyltransferase-like protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.883 |
A0A1Y2D869 | A0A1Y2DFE4 | Phosphoribosyltransferase-like protein. | Glutamine amidotransferase type-1 domain-containing protein. | 0.586 |
A0A1Y2D869 | A0A1Y2DUL4 | Phosphoribosyltransferase-like protein. | Uncharacterized protein. | 0.933 |
A0A1Y2D869 | A0A1Y2E380 | Phosphoribosyltransferase-like protein. | Diphthami_syn_2 domain-containing protein. | 0.845 |
A0A1Y2D869 | A0A1Y2EDY1 | Phosphoribosyltransferase-like protein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.586 |
A0A1Y2D869 | A0A1Y2EKG4 | Phosphoribosyltransferase-like protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.862 |
A0A1Y2DFE4 | A0A1Y2D5M7 | Glutamine amidotransferase type-1 domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.826 |
A0A1Y2DFE4 | A0A1Y2D869 | Glutamine amidotransferase type-1 domain-containing protein. | Phosphoribosyltransferase-like protein. | 0.586 |
A0A1Y2DFE4 | A0A1Y2DIP4 | Glutamine amidotransferase type-1 domain-containing protein. | Glutamate 5-kinase. | 0.868 |
A0A1Y2DFE4 | A0A1Y2DUL4 | Glutamine amidotransferase type-1 domain-containing protein. | Uncharacterized protein. | 0.881 |
A0A1Y2DFE4 | A0A1Y2E1V4 | Glutamine amidotransferase type-1 domain-containing protein. | FAD-binding PCMH-type domain-containing protein. | 0.586 |
A0A1Y2DFE4 | A0A1Y2E9V2 | Glutamine amidotransferase type-1 domain-containing protein. | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. | 0.794 |
A0A1Y2DFE4 | A0A1Y2EKG4 | Glutamine amidotransferase type-1 domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.858 |