A0A1Y2DY00 protein (Pseudomassariella vexata)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

A0A1Y2DY00

Mo25-like protein. (377 aa)

Predicted Functional Partners:

A0A1Y2E3K2

0.918

A0A1Y2EJZ3

0.918

A0A1Y2DDX3

0.866

A0A1Y2E1U8

0.864

A0A1Y2EI67

0.813

A0A1Y2DXF3

0.797

A0A1Y2E0N1

0.749

A0A1Y2DDD7

0.722

A0A1Y2DF43

0.722

A0A1Y2DPY0

0.722

Your Current Organism:

Pseudomassariella vexata

NCBI taxonomy Id: 1141098
Other names: CBS 129021, Didymella vexata, Didymosphaeria vexata, Leiosphaerella vexata, P. vexata, WU 31333

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1Y2DDD7	A0A1Y2DF43	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.795
A0A1Y2DDD7	A0A1Y2DY00	Non-specific serine/threonine protein kinase.	Mo25-like protein.	0.722
A0A1Y2DDD7	A0A1Y2E0N1	Non-specific serine/threonine protein kinase.	AMPK1_CBM domain-containing protein.	0.683
A0A1Y2DDD7	A0A1Y2EI67	Non-specific serine/threonine protein kinase.	5'-AMP-activated protein kinase beta subunit, interation domain-domain-containing protein.	0.988
A0A1Y2DDX3	A0A1Y2DY00	Kinase-like domain-containing protein.	Mo25-like protein.	0.866
A0A1Y2DF43	A0A1Y2DDD7	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.795
A0A1Y2DF43	A0A1Y2DY00	Uncharacterized protein.	Mo25-like protein.	0.722
A0A1Y2DF43	A0A1Y2E0N1	Uncharacterized protein.	AMPK1_CBM domain-containing protein.	0.683
A0A1Y2DF43	A0A1Y2EI67	Uncharacterized protein.	5'-AMP-activated protein kinase beta subunit, interation domain-domain-containing protein.	0.969
A0A1Y2DPY0	A0A1Y2DY00	Non-specific serine/threonine protein kinase.	Mo25-like protein.	0.722
A0A1Y2DPY0	A0A1Y2E0N1	Non-specific serine/threonine protein kinase.	AMPK1_CBM domain-containing protein.	0.683
A0A1Y2DPY0	A0A1Y2EI67	Non-specific serine/threonine protein kinase.	5'-AMP-activated protein kinase beta subunit, interation domain-domain-containing protein.	0.945
A0A1Y2DXF3	A0A1Y2DY00	SWIB domain-containing protein.	Mo25-like protein.	0.797
A0A1Y2DY00	A0A1Y2DDD7	Mo25-like protein.	Non-specific serine/threonine protein kinase.	0.722
A0A1Y2DY00	A0A1Y2DDX3	Mo25-like protein.	Kinase-like domain-containing protein.	0.866
A0A1Y2DY00	A0A1Y2DF43	Mo25-like protein.	Uncharacterized protein.	0.722
A0A1Y2DY00	A0A1Y2DPY0	Mo25-like protein.	Non-specific serine/threonine protein kinase.	0.722
A0A1Y2DY00	A0A1Y2DXF3	Mo25-like protein.	SWIB domain-containing protein.	0.797
A0A1Y2DY00	A0A1Y2E0N1	Mo25-like protein.	AMPK1_CBM domain-containing protein.	0.749
A0A1Y2DY00	A0A1Y2E1U8	Mo25-like protein.	Kinase-like domain-containing protein.	0.864

page 1 of 2

Network Stats

number of nodes:

8

number of edges:

21

average node degree:

5.25

avg. local clustering coefficient:

0.925

expected number of edges:

7

PPI enrichment p-value:

1.98e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009082

Branched-chain amino acid biosynthetic process

8 of 14

2.22

5.61

2.59e-13

GO:0009098

Leucine biosynthetic process

5 of 8

2.25

3.67

3.28e-08

GO:0009097

Isoleucine biosynthetic process

4 of 7

2.22

2.84

2.13e-06

GO:1901607

Alpha-amino acid biosynthetic process

8 of 72

1.5

2.47

7.45e-09

GO:0009099

Valine biosynthetic process

3 of 4

2.33

2.19

6.74e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003861

3-isopropylmalate dehydratase activity

2 of 2

2.46

0.77

0.0403

GO:0016836

Hydro-lyase activity

3 of 29

1.47

0.67

0.0403

GO:0000287

Magnesium ion binding

4 of 64

1.25

0.62

0.0403

GO:0019842

Vitamin binding

3 of 39

1.34

0.62

0.0468

GO:0016829

Lyase activity

4 of 103

1.05

0.53

0.0468

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009316

3-isopropylmalate dehydratase complex

2 of 2

2.46

1.43

0.0023

GO:0005829

Cytosol

8 of 308

0.87

0.79

0.00016

GO:0005737

Cytoplasm

11 of 1058

0.48

0.4

0.00043

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1004

2-Oxocarboxylic acid metabolism, and Aspartate family amino acid biosynthetic process

9 of 43

1.78

4.01

1.51e-12

CL:1067

C5-Branched dibasic acid metabolism

5 of 8

2.25

3.69

2.97e-08

CL:1002

Cellular amino acid biosynthetic process, and Aminotransferase, class I/classII

10 of 86

1.52

3.05

1.51e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

blep00290

Valine, leucine and isoleucine biosynthesis

10 of 13

2.34

8.38

4.80e-20

blep01210

2-Oxocarboxylic acid metabolism

8 of 26

1.95

4.69

6.24e-13

blep00770

Pantothenate and CoA biosynthesis

5 of 13

2.04

3.43

3.12e-08

blep00660

C5-Branched dibasic acid metabolism

4 of 10

2.06

2.83

1.18e-06

blep01230

Biosynthesis of amino acids

9 of 99

1.42

2.5

6.15e-11

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009316

3-isopropylmalate dehydratase complex

2 of 2

2.46

1.25

0.0050

GOCC:0005829

Cytosol

9 of 530

0.69

0.57

0.00067

GOCC:0005737

Cytoplasm

11 of 883

0.55

0.47

0.00026

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0100

Branched-chain amino acid biosynthesis

9 of 11

2.37

7.54

2.25e-17

KW-0432

Leucine biosynthesis

4 of 4

2.46

3.33

3.93e-07

KW-0456

Lyase

4 of 69

1.22

0.91

0.0041

KW-0460

Magnesium

4 of 102

1.05

0.69

0.0117

KW-0479

Metal-binding

6 of 276

0.8

0.57

0.0064

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