STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2EBT5Cut8 six-helix bundle-domain-containing protein; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins. (279 aa)    
Predicted Functional Partners:
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]
    
 0.930
A0A1Y2E9Z0
60S ribosomal protein l7-like protein.
   
 0.810
A0A1Y2E8R3
WD40-repeat-containing domain protein.
   
  0.798
A0A1Y2DSD9
Mysoin-binding motif of peroxisomes-domain-containing protein.
  
 0.781
A0A1Y2DSF6
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.781
A0A1Y2E3S5
Uncharacterized protein.
 
   
  0.777
A0A1Y2DCJ5
rRNA-processing arch domain-domain-containing protein.
 
 
    0.754
A0A1Y2DI27
CLP1_P domain-containing protein.
   
 
  0.714
A0A1Y2E717
Rix1 complex component.
   
 
  0.714
A0A1Y2E3K4
Ribonuclease H-like domain-containing protein.
   
 0.698
Your Current Organism:
Pseudomassariella vexata
NCBI taxonomy Id: 1141098
Other names: CBS 129021, Didymella vexata, Didymosphaeria vexata, Leiosphaerella vexata, P. vexata, WU 31333
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