node1 | node2 | node1 annotation | node2 annotation | score |
A0A1Y2DJ14 | A0A1Y2E4D2 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Protein kinase domain-containing protein. | 0.416 |
A0A1Y2DJ14 | A0A1Y2E4X8 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Ubiquitin family protein. | 0.657 |
A0A1Y2DJ14 | A0A1Y2EBA8 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.681 |
A0A1Y2DJ14 | A0A1Y2EEC3 | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | Kinase-like domain-containing protein. | 0.703 |
A0A1Y2DUI4 | A0A1Y2E4D2 | Uncharacterized protein. | Protein kinase domain-containing protein. | 0.846 |
A0A1Y2DUI4 | A0A1Y2EEC3 | Uncharacterized protein. | Kinase-like domain-containing protein. | 0.860 |
A0A1Y2DUI4 | A0A1Y2EKJ1 | Uncharacterized protein. | P-loop containing nucleoside triphosphate hydrolase protein. | 0.980 |
A0A1Y2E4D2 | A0A1Y2DJ14 | Protein kinase domain-containing protein. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.416 |
A0A1Y2E4D2 | A0A1Y2DUI4 | Protein kinase domain-containing protein. | Uncharacterized protein. | 0.846 |
A0A1Y2E4D2 | A0A1Y2E744 | Protein kinase domain-containing protein. | Non-specific serine/threonine protein kinase. | 0.923 |
A0A1Y2E4D2 | A0A1Y2EBA8 | Protein kinase domain-containing protein. | Ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.504 |
A0A1Y2E4D2 | A0A1Y2EBB2 | Protein kinase domain-containing protein. | Cell division control protein. | 0.957 |
A0A1Y2E4D2 | A0A1Y2EEC3 | Protein kinase domain-containing protein. | Kinase-like domain-containing protein. | 0.937 |
A0A1Y2E4D2 | A0A1Y2EKJ1 | Protein kinase domain-containing protein. | P-loop containing nucleoside triphosphate hydrolase protein. | 0.979 |
A0A1Y2E4X8 | A0A1Y2DJ14 | Ubiquitin family protein. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.657 |
A0A1Y2E4X8 | A0A1Y2EBA8 | Ubiquitin family protein. | Ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.999 |
A0A1Y2E4X8 | A0A1Y2EEC3 | Ubiquitin family protein. | Kinase-like domain-containing protein. | 0.739 |
A0A1Y2E643 | A0A1Y2EEC3 | WD40-repeat-containing domain protein. | Kinase-like domain-containing protein. | 0.936 |
A0A1Y2E744 | A0A1Y2E4D2 | Non-specific serine/threonine protein kinase. | Protein kinase domain-containing protein. | 0.923 |
A0A1Y2E744 | A0A1Y2EBB2 | Non-specific serine/threonine protein kinase. | Cell division control protein. | 0.987 |