STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmECytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (159 aa)    
Predicted Functional Partners:
ccmC
Heme ABC transporter membrane protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 
 0.999
OOA_01135
Heme lyase subunit CcmF; COG1138 Cytochrome c biogenesis factor.
 
 
 0.982
OOA_01125
Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
 
 
 0.979
OOA_01140
Thiol:disulfide interchange protein DsbE; COG0526 Thiol-disulfide isomerase and thioredoxins.
 
  
 0.975
OOA_01145
Heme lyase subunit CcmH; Possible subunit of a heme lyase.
 
  
 0.964
OOA_17276
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
 
 0.940
ccmA
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
 
 0.904
OOA_01150
Hypothetical protein.
  
    0.458
Your Current Organism:
Providencia burhodogranariea
NCBI taxonomy Id: 1141662
Other names: P. burhodogranariea DSM 19968, Providencia burhodogranariea DSM 19968, Providencia burhodogranariea str. B, Providencia burhodogranariea str. DSM 19968, Providencia burhodogranariea strain DSM 19968
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