node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAM03616.1 | BAM03617.1 | PSMK_14570 | PSMK_14580 | Methionine synthase; Fragment. | Methionine synthase; Fragment. | 0.999 |
BAM03616.1 | ahcY | PSMK_14570 | PSMK_03450 | Methionine synthase; Fragment. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.920 |
BAM03616.1 | folA | PSMK_14570 | PSMK_14210 | Methionine synthase; Fragment. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.900 |
BAM03616.1 | gcvT | PSMK_14570 | PSMK_21250 | Methionine synthase; Fragment. | Aminomethyltransferase; Protein synonym:glycine cleavage system T protein. | 0.909 |
BAM03616.1 | glyA | PSMK_14570 | PSMK_03930 | Methionine synthase; Fragment. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.915 |
BAM03616.1 | hom | PSMK_14570 | PSMK_12590 | Methionine synthase; Fragment. | Homoserine dehydrogenase. | 0.859 |
BAM03616.1 | metF | PSMK_14570 | PSMK_13730 | Methionine synthase; Fragment. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.975 |
BAM03616.1 | metK | PSMK_14570 | PSMK_24540 | Methionine synthase; Fragment. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.919 |
BAM03616.1 | metY | PSMK_14570 | PSMK_21170 | Methionine synthase; Fragment. | Protein synonym:O-acetylhomoserine sulfhydrylase. | 0.917 |
BAM03616.1 | purU | PSMK_14570 | PSMK_05420 | Methionine synthase; Fragment. | Formyltetrahydrofolate deformylase. | 0.912 |
BAM03617.1 | BAM03616.1 | PSMK_14580 | PSMK_14570 | Methionine synthase; Fragment. | Methionine synthase; Fragment. | 0.999 |
BAM03617.1 | ahcY | PSMK_14580 | PSMK_03450 | Methionine synthase; Fragment. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.948 |
BAM03617.1 | folA | PSMK_14580 | PSMK_14210 | Methionine synthase; Fragment. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.929 |
BAM03617.1 | gcvT | PSMK_14580 | PSMK_21250 | Methionine synthase; Fragment. | Aminomethyltransferase; Protein synonym:glycine cleavage system T protein. | 0.950 |
BAM03617.1 | glyA | PSMK_14580 | PSMK_03930 | Methionine synthase; Fragment. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.936 |
BAM03617.1 | hom | PSMK_14580 | PSMK_12590 | Methionine synthase; Fragment. | Homoserine dehydrogenase. | 0.927 |
BAM03617.1 | metF | PSMK_14580 | PSMK_13730 | Methionine synthase; Fragment. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.997 |
BAM03617.1 | metK | PSMK_14580 | PSMK_24540 | Methionine synthase; Fragment. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.947 |
BAM03617.1 | metY | PSMK_14580 | PSMK_21170 | Methionine synthase; Fragment. | Protein synonym:O-acetylhomoserine sulfhydrylase. | 0.948 |
BAM03617.1 | purU | PSMK_14580 | PSMK_05420 | Methionine synthase; Fragment. | Formyltetrahydrofolate deformylase. | 0.926 |