STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAM03617.1Methionine synthase; Fragment. (640 aa)    
Predicted Functional Partners:
BAM03616.1
Methionine synthase; Fragment.
 
 0.999
metF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.997
gcvT
Aminomethyltransferase; Protein synonym:glycine cleavage system T protein.
  
 
 0.950
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.948
metY
Protein synonym:O-acetylhomoserine sulfhydrylase.
  
 
 0.948
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.947
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.936
folA
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
    
 0.929
hom
Homoserine dehydrogenase.
  
 
 0.927
purU
Formyltetrahydrofolate deformylase.
 
  
 0.926
Your Current Organism:
Phycisphaera mikurensis
NCBI taxonomy Id: 1142394
Other names: P. mikurensis NBRC 102666, Phycisphaera mikurensis FYK2301M01, Phycisphaera mikurensis NBRC 102666, Phycisphaera mikurensis str. NBRC 102666, Phycisphaera mikurensis strain NBRC 102666, planctomycete FYK2301M01
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