node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAM05227.1 | glyA | PSMK_30680 | PSMK_03930 | Aminotransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.931 |
BAM05227.1 | pssA | PSMK_30680 | PSMK_02530 | Aminotransferase. | Putative CDP-diacylglycerol--serine O-phosphatidyltransferase; Protein synonym:phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
BAM05227.1 | trpA | PSMK_30680 | PSMK_15810 | Aminotransferase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.902 |
BAM05227.1 | trpB | PSMK_30680 | PSMK_24640 | Aminotransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.911 |
glyA | BAM05227.1 | PSMK_03930 | PSMK_30680 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminotransferase. | 0.931 |
glyA | pssA | PSMK_03930 | PSMK_02530 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative CDP-diacylglycerol--serine O-phosphatidyltransferase; Protein synonym:phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
glyA | trpA | PSMK_03930 | PSMK_15810 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.927 |
glyA | trpB | PSMK_03930 | PSMK_24640 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.922 |
pabA | pabB | PSMK_15700 | PSMK_16470 | Para-aminobenzoate synthase glutamine amidotransferase component II. | Putative para-aminobenzoate synthase component I. | 0.999 |
pabA | trpA | PSMK_15700 | PSMK_15810 | Para-aminobenzoate synthase glutamine amidotransferase component II. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.969 |
pabA | trpB | PSMK_15700 | PSMK_24640 | Para-aminobenzoate synthase glutamine amidotransferase component II. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.961 |
pabA | trpC | PSMK_15700 | PSMK_15840 | Para-aminobenzoate synthase glutamine amidotransferase component II. | Putative indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.998 |
pabA | trpD | PSMK_15700 | PSMK_10650 | Para-aminobenzoate synthase glutamine amidotransferase component II. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.998 |
pabA | trpE | PSMK_15700 | PSMK_02840 | Para-aminobenzoate synthase glutamine amidotransferase component II. | Anthranilate synthase component I. | 0.999 |
pabA | trpF | PSMK_15700 | PSMK_16810 | Para-aminobenzoate synthase glutamine amidotransferase component II. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.997 |
pabB | pabA | PSMK_16470 | PSMK_15700 | Putative para-aminobenzoate synthase component I. | Para-aminobenzoate synthase glutamine amidotransferase component II. | 0.999 |
pabB | trpA | PSMK_16470 | PSMK_15810 | Putative para-aminobenzoate synthase component I. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.926 |
pabB | trpB | PSMK_16470 | PSMK_24640 | Putative para-aminobenzoate synthase component I. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.857 |
pabB | trpC | PSMK_16470 | PSMK_15840 | Putative para-aminobenzoate synthase component I. | Putative indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.983 |
pabB | trpD | PSMK_16470 | PSMK_10650 | Putative para-aminobenzoate synthase component I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.992 |