BAM05143.1 protein (Phycisphaera mikurensis)

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Known Interactions

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experimentally determined

Predicted Interactions

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[Homology]

Score

BAM05143.1

Putative sialic acid synthase. (352 aa)

Predicted Functional Partners:

BAM02523.1

0.984

BAM02522.1

0.943

BAM05261.1

0.838

BAM02525.1

0.795

BAM05142.1

0.642

kdsC

0.603

rmlB

0.598

BAM05141.1

0.537

BAM03908.1

0.530

BAM05144.1

0.486

Your Current Organism:

Phycisphaera mikurensis

NCBI taxonomy Id: 1142394
Other names: P. mikurensis NBRC 102666, Phycisphaera mikurensis FYK2301M01, Phycisphaera mikurensis NBRC 102666, Phycisphaera mikurensis str. NBRC 102666, Phycisphaera mikurensis strain NBRC 102666, planctomycete FYK2301M01

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAM02522.1	BAM02523.1	PSMK_03630	PSMK_03640	Putative UDP-N-acetylglucosamine 2-epimerase.	Putative CMP-sialic acid synthase; Protein synonym:N-acylneuraminate cytidylyltransferase.	0.961
BAM02522.1	BAM02525.1	PSMK_03630	PSMK_03660	Putative UDP-N-acetylglucosamine 2-epimerase.	Hypothetical protein.	0.918
BAM02522.1	BAM03908.1	PSMK_03630	PSMK_17490	Putative UDP-N-acetylglucosamine 2-epimerase.	Putative acyltransferase.	0.616
BAM02522.1	BAM05143.1	PSMK_03630	PSMK_29840	Putative UDP-N-acetylglucosamine 2-epimerase.	Putative sialic acid synthase.	0.943
BAM02522.1	BAM05261.1	PSMK_03630	PSMK_31020	Putative UDP-N-acetylglucosamine 2-epimerase.	Hypothetical protein.	0.735
BAM02522.1	rmlB	PSMK_03630	PSMK_04210	Putative UDP-N-acetylglucosamine 2-epimerase.	dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.642
BAM02523.1	BAM02522.1	PSMK_03640	PSMK_03630	Putative CMP-sialic acid synthase; Protein synonym:N-acylneuraminate cytidylyltransferase.	Putative UDP-N-acetylglucosamine 2-epimerase.	0.961
BAM02523.1	BAM02525.1	PSMK_03640	PSMK_03660	Putative CMP-sialic acid synthase; Protein synonym:N-acylneuraminate cytidylyltransferase.	Hypothetical protein.	0.928
BAM02523.1	BAM03908.1	PSMK_03640	PSMK_17490	Putative CMP-sialic acid synthase; Protein synonym:N-acylneuraminate cytidylyltransferase.	Putative acyltransferase.	0.447
BAM02523.1	BAM05143.1	PSMK_03640	PSMK_29840	Putative CMP-sialic acid synthase; Protein synonym:N-acylneuraminate cytidylyltransferase.	Putative sialic acid synthase.	0.984
BAM02523.1	BAM05261.1	PSMK_03640	PSMK_31020	Putative CMP-sialic acid synthase; Protein synonym:N-acylneuraminate cytidylyltransferase.	Hypothetical protein.	0.773
BAM02525.1	BAM02522.1	PSMK_03660	PSMK_03630	Hypothetical protein.	Putative UDP-N-acetylglucosamine 2-epimerase.	0.918
BAM02525.1	BAM02523.1	PSMK_03660	PSMK_03640	Hypothetical protein.	Putative CMP-sialic acid synthase; Protein synonym:N-acylneuraminate cytidylyltransferase.	0.928
BAM02525.1	BAM03908.1	PSMK_03660	PSMK_17490	Hypothetical protein.	Putative acyltransferase.	0.410
BAM02525.1	BAM05143.1	PSMK_03660	PSMK_29840	Hypothetical protein.	Putative sialic acid synthase.	0.795
BAM02525.1	BAM05261.1	PSMK_03660	PSMK_31020	Hypothetical protein.	Hypothetical protein.	0.493
BAM03908.1	BAM02522.1	PSMK_17490	PSMK_03630	Putative acyltransferase.	Putative UDP-N-acetylglucosamine 2-epimerase.	0.616
BAM03908.1	BAM02523.1	PSMK_17490	PSMK_03640	Putative acyltransferase.	Putative CMP-sialic acid synthase; Protein synonym:N-acylneuraminate cytidylyltransferase.	0.447
BAM03908.1	BAM02525.1	PSMK_17490	PSMK_03660	Putative acyltransferase.	Hypothetical protein.	0.410
BAM03908.1	BAM05143.1	PSMK_17490	PSMK_29840	Putative acyltransferase.	Putative sialic acid synthase.	0.530

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

50

average node degree:

9.09

avg. local clustering coefficient:

0.934

expected number of edges:

16

PPI enrichment p-value:

1.74e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006096

Glycolytic process

6 of 15

1.92

3.23

3.33e-08

GO:0006091

Generation of precursor metabolites and energy

10 of 72

1.46

2.7

2.09e-11

GO:0006098

Pentose-phosphate shunt

4 of 8

2.02

2.5

6.23e-06

GO:0006006

Glucose metabolic process

4 of 12

1.84

2.16

1.86e-05

GO:0005975

Carbohydrate metabolic process

9 of 110

1.23

1.71

3.33e-08

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1451

Glycolysis, and Glyceraldehyde-3-phosphate dehydrogenase, type I

8 of 11

2.18

5.58

1.72e-13

CL:1447

Pentose phosphate pathway, and Glycolysis

10 of 31

1.83

4.69

5.80e-15

CL:1453

Glyceraldehyde-3-phosphate dehydrogenase, type I, and Glycolysis

3 of 5

2.1

1.79

0.00031

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

nae01200

Carbon metabolism

11 of 81

1.45

2.95

2.33e-14

nae00030

Pentose phosphate pathway

5 of 16

1.81

2.75

2.91e-07

nae00010

Glycolysis / Gluconeogenesis

6 of 31

1.61

2.49

1.02e-07

nae00680

Methane metabolism

4 of 16

1.72

2.05

1.70e-05

nae01230

Biosynthesis of amino acids

9 of 101

1.27

1.92

1.63e-09

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0324

Glycolysis

6 of 8

2.19

4.19

1.23e-09

KW-0312

Gluconeogenesis

2 of 5

1.92

0.74

0.0401

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02781

Glucose-6-phosphate dehydrogenase, C-terminal domain

2 of 2

2.32

0.74

0.0447

PF00479

Glucose-6-phosphate dehydrogenase, NAD binding domain

2 of 2

2.32

0.74

0.0447

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