STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PS3_11348Transcriptional regulator; Belongs to the CtsR family. (156 aa)    
Predicted Functional Partners:
PS3_9730
ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
  
 0.804
hrcA
Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
   
  
 0.693
PS3_13746
ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
  
 0.549
PS3_9731
ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
  
 0.549
PS3_15929
ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
  
 0.501
PS3_22302
Cell division initiation protein.
  
     0.486
PS3_3228
Transcriptional regulator; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.439
PS3_8978
30S ribosomal protein S1.
  
     0.434
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.418
PS3_19309
Hypothetical protein.
  
     0.414
Your Current Organism:
Lactobacillus gastricus
NCBI taxonomy Id: 1144300
Other names: L. gastricus PS3, Lactobacillus gastricus PS3, Lactobacillus gastricus str. PS3, Lactobacillus gastricus strain PS3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.