STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (219 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.957
AOE49935.1
CinA domain protein; Pfam:pfam02464 Competence-damaged protein; Belongs to the CinA family.
 
 
 0.953
rsfS
Ribosome-associated protein IOJAP; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.953
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.937
AOE50446.1
Nicotinate-nucleotide pyrophosphorylase; Pfam:pfam01729 Quinolinate phosphoribosyl transferase, C-terminal domain; Belongs to the NadC/ModD family.
    
 0.934
cobB
NAD-dependent protein deacylase; Pfam:pfam02146 Sir2 family; Belongs to the sirtuin family. Class III subfamily.
   
 0.933
AOE49029.1
HAD-superfamily hydrolase, subfamily IA, variant 3; Pfam:pfam13419 Haloacid dehalogenase-like hydrolase.
 
  
 0.918
rlmH
Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
  
  
 0.906
AOE49290.1
Pfam:pfam00293 NUDIX domain; Belongs to the Nudix hydrolase family.
     
 0.901
surE
5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
Your Current Organism:
Kangiella sediminilitoris
NCBI taxonomy Id: 1144748
Other names: CCUG 62217, K. sediminilitoris, KCTC 23892, Kangiella sediminilitoris Lee et al. 2013, Kangiella sp. BB-Mw22, strain BB-Mw22
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