STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRADO0186Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (227 aa)    
Predicted Functional Partners:
BRADO6002
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the multicopper oxidase YfiH/RL5 family.
 
  
 0.828
BRADO0279
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
  
 0.779
rlmN
Putative pyruvate formate lyase activating enzyme 2 (yfgB); Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
     0.673
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.663
rpmC
50S ribosomal protein L29; Function of strongly homologous gene; structure; Belongs to the universal ribosomal protein uL29 family.
   
    0.631
BRADO0200
Putative maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
    0.629
rpmJ
50S ribosomal protein L36; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL36 family.
  
    0.621
rplX
50S ribosomal subunit protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
    0.620
BRADO0187
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.607
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
  
 0.573
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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