STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acnAAconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (911 aa)    
Predicted Functional Partners:
BRADO0613
Putative citrate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the citrate synthase family.
 
 0.994
BRADO0614
Putative citrate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the citrate synthase family.
 
 0.993
icd
Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.992
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
 
 0.990
aceA
Isocitrate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.940
sodB
Superoxide dismutase, iron/manganese cofactor; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.905
sdhB
Succinate dehydrogenase, Fe-S protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.876
fumC
Fumarate hydratase class II (Fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 
 0.849
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.818
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
 
 
 0.810
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.