STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRADO0993Putative ABC transporter, permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (377 aa)    
Predicted Functional Partners:
BRADO0992
Putative ABC transporter, ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 
 0.957
BRADO0991
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.942
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.919
lolD
Lipoprotein-releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 
 0.774
lolD-2
Lipoprotein-releasing system (ABC transporter), ATP-binding protein lolD; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
 
 0.774
BRADO6864
Putative ABC transporter, ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
 
 0.774
BRADO0223
Conserved hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.746
BRADO2624
Putative membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
     0.637
BRADO5803
Hypothetical protein; No homology to any previously reported sequences.
  
     0.588
BRADO5235
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.479
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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