STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (227 aa)    
Predicted Functional Partners:
cysC
CysN/CysC bifunctional enzyme, ATP-sulfurylase large subunit and adenylyl sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
 
 0.999
BRADO1067
Sulfite/ferredoxin-nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
cysC-2
Putative CysN/CysC bifunctional enzyme: Sulfate adenylyltransferase (SAT) subunit 1 (N-terminal); Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 
 0.999
BRADO3794
Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.994
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.989
cysD
ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.977
cysA
Sulfate/thiosulfate ABC transporter, ATP-binding component; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
  
 0.967
cysD-2
Putative Sulfate adenylate transferase, subunit 2 (NodP-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.950
cysQ
CysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
  
 
 0.946
cysW
Sulfate/thiosulfate permease W protein (ABC superfamily, membrane); Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
  
 0.944
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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