Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BRADO1111Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (329 aa)    
Predicted Functional Partners:
BRADO1110
Putative flagellar motor protein MotB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
 
     0.950
parC
DNA topoisomerase IV, subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
 
 0.830
gyrA
DNA gyrase, subunit A, type II topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP- [...]
   
 
 0.800
acpP
Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.673
BRADO3527
Hypothetical protein; No homology to any previously reported sequences.
   
 
 0.673
acpXL
Acyl carrier protein; Function of homologous gene experimentally demonstrated in an other organism; carrier.
   
 
 0.673
BRADO5636
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
 
 0.673
BRADO6905
Putative Acyl carrier protein (ACP); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
   
 
 0.673
BRADO1109
Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.667
BRADO6005
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.625
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
Server load: medium (46%) [HD]