STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BRADO2102Aldehyde dehydrogenase family 7 member A1 homolog; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (542 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.661
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 
 0.645
adhA
Alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.592
BRADO3321
Putative zinc-containing alcohol dehydrogenase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.592
BRADO5308
Putative alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.592
adh
Alcohol dehydrogenase; Function of strongly homologous gene; enzyme.
  
 0.591
BRADO5171
Putative alcohol dehydrogenase (Zinc-binding); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.591
adhC
S-(hydroxymethyl)glutathione dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.591
BRADO6525
Histamine oxidase (EC 1.4.3.6) (Copper amine oxidase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.573
acsA
Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.571
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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