STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Experiments
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[Homology]
Score
hisB-2D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Sly1010220. (189 aa)    
Predicted Functional Partners:
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
  
 0.997
lmbP
D,D-heptose 7-phosphate kinase; Sly1013920.
 
 
 0.990
hisIE
Phosphoribosyl-AMP cyclohydrolase / Phosphoribosyl-ATP pyrophosphatase; Sly1024820; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.975
AIE75846.1
D-glycero-D-manno-heptose 1-phosphate guanosyltransferase; Sly1020530.
 0.975
hisB
Imidazoleglycerol-phosphate dehydratase; Sly2001060.
 
 
  
 0.928
cugP
Mannose-1-phosphate guanylyltransferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate.
 
 
 0.917
AIE75125.1
Hypothetical protein; Sly1010230.
       0.785
hisH
Imidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.775
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Sly2000060.
  
  
 0.732
hisF
Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.731
Your Current Organism:
Synechocystis sp. PCC6714
NCBI taxonomy Id: 1147
Other names: Aphanocapsa sp. (strain 5.3A), Aphanocapsa sp. 5-3A, Aphanocapsa sp. 5.3A, S. sp. PCC 6714, Synechocystis sp. (ATCC 27178), Synechocystis sp. (PCC 6714), Synechocystis sp. (strain PCC 6714), Synechocystis sp. ATCC 27178, Synechocystis sp. PCC 6714, Synechocystis sp. SAG 92.79, Synechocystis sp. UTCC 98, Synechocystis sp. UTEX 2470
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