| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cinA | panC | D082_07220 | D082_11030 | Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Sly3000680; Belongs to the CinA family. | Pantoate--beta-alanine ligase / Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | 0.508 |
| cinA | surE | D082_07220 | D082_16750 | Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Sly3000680; Belongs to the CinA family. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.915 |
| cinA | surE-2 | D082_07220 | D082_31270 | Molybdopterin binding motif, CinA N-terminal domain / C-terminal domain of CinA type S; Sly3000680; Belongs to the CinA family. | 5-nucleotidase SurE; Sly1005000. | 0.915 |
| dgt | surE | D082_06310 | D082_16750 | dNTP triphosphohydrolase, broad substrate specificity, subgroup 3; Sly2001640; Belongs to the dGTPase family. Type 3 subfamily. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
| dgt | surE-2 | D082_06310 | D082_31270 | dNTP triphosphohydrolase, broad substrate specificity, subgroup 3; Sly2001640; Belongs to the dGTPase family. Type 3 subfamily. | 5-nucleotidase SurE; Sly1005000. | 0.918 |
| guaA | guaB-2 | D082_10940 | D082_32460 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase, catalytic domain; Sly1021250. | 0.999 |
| guaA | panC | D082_10940 | D082_11030 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Pantoate--beta-alanine ligase / Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | 0.734 |
| guaA | purB | D082_10940 | D082_05960 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Sly2001970; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.948 |
| guaA | purH | D082_10940 | D082_27890 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase; Sly1008370. | 0.946 |
| guaA | pyrH | D082_10940 | D082_04050 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.770 |
| guaA | pyrR | D082_10940 | D082_07250 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.405 |
| guaA | surE | D082_10940 | D082_16750 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.943 |
| guaA | surE-2 | D082_10940 | D082_31270 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 5-nucleotidase SurE; Sly1005000. | 0.943 |
| guaB-2 | guaA | D082_32460 | D082_10940 | Inosine-5'-monophosphate dehydrogenase, catalytic domain; Sly1021250. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB-2 | panC | D082_32460 | D082_11030 | Inosine-5'-monophosphate dehydrogenase, catalytic domain; Sly1021250. | Pantoate--beta-alanine ligase / Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | 0.704 |
| guaB-2 | purB | D082_32460 | D082_05960 | Inosine-5'-monophosphate dehydrogenase, catalytic domain; Sly1021250. | Adenylosuccinate lyase; Sly2001970; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.862 |
| guaB-2 | purH | D082_32460 | D082_27890 | Inosine-5'-monophosphate dehydrogenase, catalytic domain; Sly1021250. | IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase; Sly1008370. | 0.964 |
| guaB-2 | pyrH | D082_32460 | D082_04050 | Inosine-5'-monophosphate dehydrogenase, catalytic domain; Sly1021250. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.414 |
| guaB-2 | surE | D082_32460 | D082_16750 | Inosine-5'-monophosphate dehydrogenase, catalytic domain; Sly1021250. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.928 |
| guaB-2 | surE-2 | D082_32460 | D082_31270 | Inosine-5'-monophosphate dehydrogenase, catalytic domain; Sly1021250. | 5-nucleotidase SurE; Sly1005000. | 0.928 |