node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argG | sll0990 | gene:10500613 | gene:10498026 | Argininosuccinate synthetase; ORF_ID:slr0585. | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.739 |
argG | slr1192 | gene:10500613 | gene:10500612 | Argininosuccinate synthetase; ORF_ID:slr0585. | Zinc-containing alcohol dehydrogenase family; ORF_ID:slr1192. | 0.461 |
sll0051 | sll0990 | gene:10499800 | gene:10498026 | ORF_ID:sll0051; hypothetical protein. | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.434 |
sll0176 | sll0990 | gene:10499544 | gene:10498026 | ORF_ID:sll0176; unknown protein. | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.800 |
sll0176 | sll0992 | gene:10499544 | gene:10498025 | ORF_ID:sll0176; unknown protein. | Esterase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.714 |
sll0990 | argG | gene:10498026 | gene:10500613 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Argininosuccinate synthetase; ORF_ID:slr0585. | 0.739 |
sll0990 | sll0051 | gene:10498026 | gene:10499800 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | ORF_ID:sll0051; hypothetical protein. | 0.434 |
sll0990 | sll0176 | gene:10498026 | gene:10499544 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | ORF_ID:sll0176; unknown protein. | 0.800 |
sll0990 | sll0992 | gene:10498026 | gene:10498025 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Esterase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.999 |
sll0990 | sll1631 | gene:10498026 | gene:10498631 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.434 |
sll0990 | slr0091 | gene:10498026 | gene:10500068 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | 0.991 |
sll0990 | slr0942 | gene:10498026 | gene:10499278 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde reductase; Aldo/keto reductase with broad substrate spectrum. Catalyzes the NADPH-dependent reduction of aldehyde- and ketone-groups of different classes of carbonyl compounds to the corresponding alcohols. Highest enzymatic efficiency is observed with 4-oxonon-2-enal (4-ONE) and 4-hydroxynon-2-enal (4-HNE), that are lipid peroxidation products, and 9,10-phenanthrenequinone (9,10-PQ), a photoproduct of phenanthrene that is one of the most prevalent polycyclic aromatic hydrocarbons in the environment. Is also active on sugar-derived reactive carbonyls such as methylglyoxal (MG) [...] | 0.994 |
sll0990 | slr1161 | gene:10498026 | gene:10499206 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | ORF_ID:slr1161; unknown protein. | 0.434 |
sll0990 | slr1192 | gene:10498026 | gene:10500612 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Zinc-containing alcohol dehydrogenase family; ORF_ID:slr1192. | 0.982 |
sll0990 | smtB | gene:10498026 | gene:10500210 | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Transcriptional repressor; Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ZiaA-mediated efflux of excess zinc into the periplasm. | 0.549 |
sll0992 | sll0176 | gene:10498025 | gene:10499544 | Esterase; Serine hydrolase involved in the detoxification of formaldehyde. | ORF_ID:sll0176; unknown protein. | 0.714 |
sll0992 | sll0990 | gene:10498025 | gene:10498026 | Esterase; Serine hydrolase involved in the detoxification of formaldehyde. | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.999 |
sll1631 | sll0990 | gene:10498631 | gene:10498026 | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.434 |
slr0091 | sll0990 | gene:10500068 | gene:10498026 | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.991 |
slr0091 | slr0942 | gene:10500068 | gene:10499278 | Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family. | Aldehyde reductase; Aldo/keto reductase with broad substrate spectrum. Catalyzes the NADPH-dependent reduction of aldehyde- and ketone-groups of different classes of carbonyl compounds to the corresponding alcohols. Highest enzymatic efficiency is observed with 4-oxonon-2-enal (4-ONE) and 4-hydroxynon-2-enal (4-HNE), that are lipid peroxidation products, and 9,10-phenanthrenequinone (9,10-PQ), a photoproduct of phenanthrene that is one of the most prevalent polycyclic aromatic hydrocarbons in the environment. Is also active on sugar-derived reactive carbonyls such as methylglyoxal (MG) [...] | 0.982 |