node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alr | merR-2 | gene:10500014 | gene:10500221 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Nitrilase; ORF_ID:sll0784. | 0.803 |
alr | murD | gene:10500014 | gene:10498580 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.788 |
alr | murI | gene:10500014 | gene:10498653 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.615 |
alr | slr0402 | gene:10500014 | gene:10499414 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.481 |
gltB-2 | murD | gene:10500464 | gene:10498580 | Ferredoxin-dependent glutamate synthase; ORF_ID:sll1499; Belongs to the glutamate synthase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.425 |
gltB-2 | murI | gene:10500464 | gene:10498653 | Ferredoxin-dependent glutamate synthase; ORF_ID:sll1499; Belongs to the glutamate synthase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.607 |
gltB-2 | purL-2 | gene:10500464 | gene:10500103 | Ferredoxin-dependent glutamate synthase; ORF_ID:sll1499; Belongs to the glutamate synthase family. | Phosphoribosyl formylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.800 |
gltB-2 | slr2079 | gene:10500464 | gene:10498836 | Ferredoxin-dependent glutamate synthase; ORF_ID:sll1499; Belongs to the glutamate synthase family. | Glutaminase; ORF_ID:slr2079; unknown protein; Belongs to the glutaminase family. | 0.879 |
merR-2 | alr | gene:10500221 | gene:10500014 | Nitrilase; ORF_ID:sll0784. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.803 |
merR-2 | murI | gene:10500221 | gene:10498653 | Nitrilase; ORF_ID:sll0784. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.808 |
merR-2 | purL-2 | gene:10500221 | gene:10500103 | Nitrilase; ORF_ID:sll0784. | Phosphoribosyl formylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.808 |
merR-2 | slr2079 | gene:10500221 | gene:10498836 | Nitrilase; ORF_ID:sll0784. | Glutaminase; ORF_ID:slr2079; unknown protein; Belongs to the glutaminase family. | 0.803 |
murD | alr | gene:10498580 | gene:10500014 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.788 |
murD | gltB-2 | gene:10498580 | gene:10500464 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Ferredoxin-dependent glutamate synthase; ORF_ID:sll1499; Belongs to the glutamate synthase family. | 0.425 |
murD | murI | gene:10498580 | gene:10498653 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.969 |
murD | purL-2 | gene:10498580 | gene:10500103 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Phosphoribosyl formylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.900 |
murD | slr2079 | gene:10498580 | gene:10498836 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glutaminase; ORF_ID:slr2079; unknown protein; Belongs to the glutaminase family. | 0.900 |
murI | alr | gene:10498653 | gene:10500014 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.615 |
murI | gltB-2 | gene:10498653 | gene:10500464 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Ferredoxin-dependent glutamate synthase; ORF_ID:sll1499; Belongs to the glutamate synthase family. | 0.607 |
murI | merR-2 | gene:10498653 | gene:10500221 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Nitrilase; ORF_ID:sll0784. | 0.808 |