node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
glmU | sll0154 | gene:10500362 | gene:10499570 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.538 |
leuA-2 | sll0154 | gene:10499571 | gene:10499570 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.503 |
lytR | sll0154 | gene:10499095 | gene:10499570 | Membrane bound protein; ORF_ID:sll1872. | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.638 |
ntcA | sll0154 | gene:10498881 | gene:10499570 | Global nitrogen regulator; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.454 |
psr | sll0154 | gene:10498474 | gene:10499570 | Regulation of penicillin binding protein 5 production; ORF_ID:slr0883. | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.572 |
sll0154 | glmU | gene:10499570 | gene:10500362 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.538 |
sll0154 | leuA-2 | gene:10499570 | gene:10499571 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.503 |
sll0154 | lytR | gene:10499570 | gene:10499095 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Membrane bound protein; ORF_ID:sll1872. | 0.638 |
sll0154 | ntcA | gene:10499570 | gene:10498881 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Global nitrogen regulator; Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. | 0.454 |
sll0154 | psr | gene:10499570 | gene:10498474 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Regulation of penicillin binding protein 5 production; ORF_ID:slr0883. | 0.572 |
sll0154 | sll0602 | gene:10499570 | gene:10499868 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | ORF_ID:sll0602; unknown protein. | 0.450 |
sll0154 | sll0832 | gene:10499570 | gene:10500018 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Putative pre-16S rRNA nuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.403 |
sll0154 | sll1033 | gene:10499570 | gene:10497627 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | ORF_ID:sll1033; unknown protein. | 0.450 |
sll0154 | sll1771 | gene:10499570 | gene:10498538 | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | ORF_ID:sll1771; hypothetical protein. | 0.450 |
sll0602 | sll0154 | gene:10499868 | gene:10499570 | ORF_ID:sll0602; unknown protein. | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.450 |
sll0602 | sll1033 | gene:10499868 | gene:10497627 | ORF_ID:sll0602; unknown protein. | ORF_ID:sll1033; unknown protein. | 0.518 |
sll0832 | sll0154 | gene:10500018 | gene:10499570 | Putative pre-16S rRNA nuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.403 |
sll1033 | sll0154 | gene:10497627 | gene:10499570 | ORF_ID:sll1033; unknown protein. | Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.450 |
sll1033 | sll0602 | gene:10497627 | gene:10499868 | ORF_ID:sll1033; unknown protein. | ORF_ID:sll0602; unknown protein. | 0.518 |
sll1033 | sll1771 | gene:10497627 | gene:10498538 | ORF_ID:sll1033; unknown protein. | ORF_ID:sll1771; hypothetical protein. | 0.522 |