STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sll1558Mannose-1-phosphate guanyltransferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. Is highly specific since it cannot use other NTPs such as dTTP, CTP, ATP, and GTP, and other sugar-1P such as GlcNAc-1P, Gal-1P, and Man-1P, as substrates. Has probably a central and essential role as the substrate supplier for galactolipid synthesis; galactolipids are major constituents of the photosynthetic thylakoid membrane and important for photosynthetic activity; Belongs to the CugP-type UDP-glucose pyrophosphorylase family. (388 aa)    
Predicted Functional Partners:
sll1496
Mannose-1-phosphate guanyltransferase; ORF_ID:sll1496.
 
 
0.935
rfbM
GDP-mannose pyrophosphorylase; ORF_ID:sll1370.
  
 
 0.926
hisB
Imidazoleglycerol-phosphate dehydratase; ORF_ID:sll0084.
 
 
 0.918
rfbD
GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
    
 0.905
yefA
GDP-D-mannose dehydratase; ORF_ID:slr1072; gene:yefA or rfbD.
    
 0.905
slr0207
ORF_ID:slr0207; unknown protein.
     
 0.814
slr1508
ORF_ID:slr1508; unknown protein.
  
 
 0.766
sll1376
Monoglucosyldiacylglycerol epimerase; Involved in the biosynthesis of galactolipids found in the photosynthetic membranes. Catalyzes the isomerization of monoglucosyldiacylglycerol (GlcDG) to yield monogalactosyldiacylglycerol (MGDG); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.727
rfbA
Glucose-1-phosphate thymidylyltransferase; ORF_ID:sll0207.
 
  
0.699
galE
UDP-glucose-4-epimerase; ORF_ID:slr1067; gene:galE or galD; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
  
 0.695
Your Current Organism:
Synechocystis sp. PCC6803
NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B
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