sll1527 protein (Synechocystis sp. PCC6803) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

sll1527

ORF_ID:sll1527; unknown protein. (1168 aa)

Predicted Functional Partners:

sll1526

0.985

sll0470

0.965

sll1528

0.949

ssl1378

0.942

sll1530

0.921

sll0729

0.839

slr1028

0.757

sll1531

0.752

slr0408

0.752

slr0521

0.736

Your Current Organism:

Synechocystis sp. PCC6803

NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
sll0470	sll0729	gene:10500107	gene:10500525	ORF_ID:sll0470; unknown protein.	Modification methylase; ORF_ID:sll0729.	0.829
sll0470	sll1526	gene:10500107	gene:10499332	ORF_ID:sll0470; unknown protein.	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	0.961
sll0470	sll1527	gene:10500107	gene:10499331	ORF_ID:sll0470; unknown protein.	ORF_ID:sll1527; unknown protein.	0.965
sll0470	ssl1378	gene:10500107	gene:10500524	ORF_ID:sll0470; unknown protein.	ORF_ID:ssl1378; unknown protein.	0.901
sll0729	sll0470	gene:10500525	gene:10500107	Modification methylase; ORF_ID:sll0729.	ORF_ID:sll0470; unknown protein.	0.829
sll0729	sll1526	gene:10500525	gene:10499332	Modification methylase; ORF_ID:sll0729.	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	0.829
sll0729	sll1527	gene:10500525	gene:10499331	Modification methylase; ORF_ID:sll0729.	ORF_ID:sll1527; unknown protein.	0.839
sll0729	ssl1378	gene:10500525	gene:10500524	Modification methylase; ORF_ID:sll0729.	ORF_ID:ssl1378; unknown protein.	0.990
sll1526	sll0470	gene:10499332	gene:10500107	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	ORF_ID:sll0470; unknown protein.	0.961
sll1526	sll0729	gene:10499332	gene:10500525	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	Modification methylase; ORF_ID:sll0729.	0.829
sll1526	sll1527	gene:10499332	gene:10499331	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	ORF_ID:sll1527; unknown protein.	0.985
sll1526	sll1528	gene:10499332	gene:10499330	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	ORF_ID:sll1528; unknown protein.	0.527
sll1526	sll1530	gene:10499332	gene:10499329	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	ORF_ID:sll1530; unknown protein.	0.498
sll1526	sll1531	gene:10499332	gene:10499328	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	ORF_ID:sll1531; unknown protein.	0.486
sll1526	ssl1378	gene:10499332	gene:10500524	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	ORF_ID:ssl1378; unknown protein.	0.913
sll1527	sll0470	gene:10499331	gene:10500107	ORF_ID:sll1527; unknown protein.	ORF_ID:sll0470; unknown protein.	0.965
sll1527	sll0729	gene:10499331	gene:10500525	ORF_ID:sll1527; unknown protein.	Modification methylase; ORF_ID:sll0729.	0.839
sll1527	sll1526	gene:10499331	gene:10499332	ORF_ID:sll1527; unknown protein.	ORF_ID:sll1526; unknown protein; To R.prowazekii RP789, RP027 and RP028.	0.985
sll1527	sll1528	gene:10499331	gene:10499330	ORF_ID:sll1527; unknown protein.	ORF_ID:sll1528; unknown protein.	0.949
sll1527	sll1530	gene:10499331	gene:10499329	ORF_ID:sll1527; unknown protein.	ORF_ID:sll1530; unknown protein.	0.921

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

28

PPI enrichment p-value:

2.57e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 102

1.49

2.84

8.60e-12

GO:0009987

Cellular process

11 of 1718

0.31

0.25

0.0204

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 52

1.74

3.82

2.54e-12

GO:0019843

rRNA binding

4 of 42

1.48

1.21

0.0015

GO:0003723

RNA binding

5 of 107

1.17

0.95

0.0018

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 57

1.7

3.75

9.05e-13

GO:0015935

Small ribosomal subunit

2 of 8

1.9

1.15

0.0055

GO:0005622

Intracellular anatomical structure

11 of 1098

0.5

0.44

5.17e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:22043294

(2011) Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.

3 of 8

2.07

1.68

0.00051

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:133

Structural constituent of ribosome

9 of 58

1.69

3.67

1.85e-12

CL:122

Ribosome, and Translation regulator activity

10 of 81

1.59

3.35

7.71e-13

CL:171

Mixed, incl. Translation regulation, and Nucleotide-binding alpha-beta plait domain superfamily

4 of 6

2.32

3.15

6.41e-07

CL:134

rRNA-binding, and EFG, domain V

6 of 31

1.79

3.01

2.57e-08

CL:136

rRNA-binding

5 of 25

1.8

2.59

7.95e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

9 of 57

1.7

3.74

1.00e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 45

1.8

4.24

3.02e-13

GOCC:0022626

Cytosolic ribosome

2 of 12

1.72

0.84

0.0221

GOCC:0044391

Ribosomal subunit

2 of 17

1.57

0.71

0.0366

GOCC:0005622

Intracellular

11 of 1069

0.51

0.44

8.89e-05

GOCC:0110165

Cellular anatomical entity

11 of 1701

0.31

0.26

0.0123

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 54

1.72

3.83

1.05e-12

KW-0699

rRNA-binding

4 of 39

1.51

1.43

0.00036

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