node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hisI | ribC | gene:10500647 | gene:10499519 | phosphoribosyl-ATP pyrophosphohydrolase:phosphoribosyl-AMP cyclohydrolase; ORF_ID:slr0608; In the C-terminal section; belongs to the PRA-PH family. | Riboflavin synthase alpha chain; ORF_ID:sll0300. | 0.804 |
hisI | ribG | gene:10500647 | gene:10499795 | phosphoribosyl-ATP pyrophosphohydrolase:phosphoribosyl-AMP cyclohydrolase; ORF_ID:slr0608; In the C-terminal section; belongs to the PRA-PH family. | Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. | 0.439 |
hisI | rpl31 | gene:10500647 | gene:10498183 | phosphoribosyl-ATP pyrophosphohydrolase:phosphoribosyl-AMP cyclohydrolase; ORF_ID:slr0608; In the C-terminal section; belongs to the PRA-PH family. | 50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.872 |
hisI | slr0876 | gene:10500647 | gene:10498463 | phosphoribosyl-ATP pyrophosphohydrolase:phosphoribosyl-AMP cyclohydrolase; ORF_ID:slr0608; In the C-terminal section; belongs to the PRA-PH family. | ORF_ID:slr0876; hypothetical protein. | 0.737 |
hitB | ribC | gene:10499521 | gene:10499519 | Iron utilization protein; ORF_ID:slr0327. | Riboflavin synthase alpha chain; ORF_ID:sll0300. | 0.428 |
hitB | slr0326 | gene:10499521 | gene:10499520 | Iron utilization protein; ORF_ID:slr0327. | ORF_ID:slr0326; unknown protein. | 0.576 |
ribA | ribC | gene:10499063 | gene:10499519 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | Riboflavin synthase alpha chain; ORF_ID:sll0300. | 0.999 |
ribA | ribG | gene:10499063 | gene:10499795 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. | 0.999 |
ribA | ribH | gene:10499063 | gene:10498433 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | Riboflavin synthase beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
ribA | rpl31 | gene:10499063 | gene:10498183 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.464 |
ribA | slr1882 | gene:10499063 | gene:10498563 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | Bifunctional riboflavin kinase/FMN adenylyltransferase; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. | 0.709 |
ribC | hisI | gene:10499519 | gene:10500647 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | phosphoribosyl-ATP pyrophosphohydrolase:phosphoribosyl-AMP cyclohydrolase; ORF_ID:slr0608; In the C-terminal section; belongs to the PRA-PH family. | 0.804 |
ribC | hitB | gene:10499519 | gene:10499521 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | Iron utilization protein; ORF_ID:slr0327. | 0.428 |
ribC | ribA | gene:10499519 | gene:10499063 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
ribC | ribG | gene:10499519 | gene:10499795 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. | 0.999 |
ribC | ribH | gene:10499519 | gene:10498433 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | Riboflavin synthase beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
ribC | rpl31 | gene:10499519 | gene:10498183 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | 50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.722 |
ribC | slr0326 | gene:10499519 | gene:10499520 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | ORF_ID:slr0326; unknown protein. | 0.560 |
ribC | slr0876 | gene:10499519 | gene:10498463 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | ORF_ID:slr0876; hypothetical protein. | 0.722 |
ribC | slr1694 | gene:10499519 | gene:10499265 | Riboflavin synthase alpha chain; ORF_ID:sll0300. | Activator of photopigment and puc expression; ORF_ID:slr1694. | 0.979 |