slr0829 protein (Synechocystis sp. PCC6803) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

slr0829

ORF_ID:slr0829; PleD gene product homologue. (829 aa)

Predicted Functional Partners:

sll1905

0.995

slr1759

0.991

slr1305

0.982

slr2104

0.982

sll1228

0.978

slr1588

0.967

slr2098

0.952

sll1672

0.945

slr1102

0.920

sll1895

0.912

Your Current Organism:

Synechocystis sp. PCC6803

NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
sll1228	sll1672	gene:10498957	gene:10497662	Hybrid sensory kinase; ORF_ID:sll1228.	Hybrid sensory kinase; ORF_ID:sll1672.	0.928
sll1228	sll1895	gene:10498957	gene:10499060	Hybrid sensory kinase; ORF_ID:sll1228.	ORF_ID:sll1895; hypothetical protein.	0.592
sll1228	sll1905	gene:10498957	gene:10498754	Hybrid sensory kinase; ORF_ID:sll1228.	Hybrid sensory kinase; ORF_ID:sll1905.	0.993
sll1228	slr0829	gene:10498957	gene:10500015	Hybrid sensory kinase; ORF_ID:sll1228.	ORF_ID:slr0829; PleD gene product homologue.	0.978
sll1228	slr1102	gene:10498957	gene:10497617	Hybrid sensory kinase; ORF_ID:sll1228.	ORF_ID:slr1102; hypothetical protein.	0.710
sll1228	slr1305	gene:10498957	gene:10497716	Hybrid sensory kinase; ORF_ID:sll1228.	Regulatory components of sensory transduction system; ORF_ID:slr1305.	0.925
sll1228	slr1588	gene:10498957	gene:10500511	Hybrid sensory kinase; ORF_ID:sll1228.	Regulatory components of sensory transduction system; ORF_ID:slr1588.	0.665
sll1228	slr1759	gene:10498957	gene:10497917	Hybrid sensory kinase; ORF_ID:sll1228.	Hybrid sensory kinase; ORF_ID:slr1759.	0.990
sll1228	slr2098	gene:10498957	gene:10498862	Hybrid sensory kinase; ORF_ID:sll1228.	Hybrid sensory kinase; ORF_ID:slr2098.	0.990
sll1228	slr2104	gene:10498957	gene:10498868	Hybrid sensory kinase; ORF_ID:sll1228.	Hybrid sensory kinase; ORF_ID:slr2104.	0.984
sll1672	sll1228	gene:10497662	gene:10498957	Hybrid sensory kinase; ORF_ID:sll1672.	Hybrid sensory kinase; ORF_ID:sll1228.	0.928
sll1672	sll1895	gene:10497662	gene:10499060	Hybrid sensory kinase; ORF_ID:sll1672.	ORF_ID:sll1895; hypothetical protein.	0.654
sll1672	sll1905	gene:10497662	gene:10498754	Hybrid sensory kinase; ORF_ID:sll1672.	Hybrid sensory kinase; ORF_ID:sll1905.	0.988
sll1672	slr0829	gene:10497662	gene:10500015	Hybrid sensory kinase; ORF_ID:sll1672.	ORF_ID:slr0829; PleD gene product homologue.	0.945
sll1672	slr1102	gene:10497662	gene:10497617	Hybrid sensory kinase; ORF_ID:sll1672.	ORF_ID:slr1102; hypothetical protein.	0.827
sll1672	slr1305	gene:10497662	gene:10497716	Hybrid sensory kinase; ORF_ID:sll1672.	Regulatory components of sensory transduction system; ORF_ID:slr1305.	0.972
sll1672	slr1588	gene:10497662	gene:10500511	Hybrid sensory kinase; ORF_ID:sll1672.	Regulatory components of sensory transduction system; ORF_ID:slr1588.	0.750
sll1672	slr1759	gene:10497662	gene:10497917	Hybrid sensory kinase; ORF_ID:sll1672.	Hybrid sensory kinase; ORF_ID:slr1759.	0.987
sll1672	slr2098	gene:10497662	gene:10498862	Hybrid sensory kinase; ORF_ID:sll1672.	Hybrid sensory kinase; ORF_ID:slr2098.	0.989
sll1672	slr2104	gene:10497662	gene:10498868	Hybrid sensory kinase; ORF_ID:sll1672.	Hybrid sensory kinase; ORF_ID:slr2104.	0.981

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Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.847

expected number of edges:

36

PPI enrichment p-value:

0.998

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009401

Phosphoenolpyruvate-dependent sugar phosphotransferase system

11 of 117

1.18

1.76

1.31e-10

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0103111

D-glucosamine PTS permease activity

7 of 44

1.41

2.0

2.62e-07

GO:0008982

protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

10 of 91

1.25

1.89

9.53e-10

GO:0016740

Transferase activity

11 of 363

0.69

0.66

1.80e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

9 of 441

0.52

0.37

0.0113

GO:0005886

Plasma membrane

8 of 389

0.52

0.37

0.0145

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1608

Import into cell

11 of 52

1.54

3.32

1.57e-14

CL:1701

Mixed, incl. CAT RNA-binding domain, and PTS system fructose IIA component

4 of 5

2.11

2.63

4.56e-06

CL:1610

Import into cell

7 of 42

1.43

2.09

1.42e-07

CL:1612

Fructose and mannose metabolism, and PTS system sorbose subfamily IIB component

6 of 34

1.46

1.93

1.95e-06

CL:1644

Mixed, incl. PTS system sorbose-specific iic component, and PTS system sorbose subfamily IIB component

3 of 7

1.84

1.5

0.00082

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00051

Fructose and mannose metabolism

7 of 56

1.31

1.72

6.76e-07

map02060

Phosphotransferase system (PTS)

11 of 130

1.14

1.66

4.74e-11

map00520

Amino sugar and nucleotide sugar metabolism

7 of 78

1.16

1.36

3.84e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005887

Integral component of plasma membrane

4 of 40

1.21

0.89

0.0045

GOCC:0005886

Plasma membrane

11 of 305

0.77

8.54e-07

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03609

PTS system sorbose-specific iic component

6 of 15

1.81

2.85

1.35e-07

PF03830

PTS system sorbose subfamily IIB component

3 of 15

1.51

0.84

0.0171

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004700

Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit

6 of 15

1.81

2.69

4.10e-07

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