slr0789 protein (Synechocystis sp. PCC6803) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

slr0789

ORF_ID:slr0789; unknown protein. (185 aa)

Predicted Functional Partners:

guaA

0.848

umuC

0.741

slr0376

0.680

ssr2016

0.549

slr0551

0.549

slr0245

0.526

cbbZp

0.441

slr0541

0.423

Your Current Organism:

Synechocystis sp. PCC6803

NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cbbZp	slr0789	gene:10498431	gene:10500199	Phosphoglycolate phosphatase; ORF_ID:sll1349.	ORF_ID:slr0789; unknown protein.	0.441
guaA	slr0551	gene:10499709	gene:10500377	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.	0.408
guaA	slr0789	gene:10499709	gene:10500199	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	ORF_ID:slr0789; unknown protein.	0.848
slr0245	slr0789	gene:10497564	gene:10500199	Acetylpolyamine aminohydolase; Putative deacetylase.	ORF_ID:slr0789; unknown protein.	0.526
slr0376	slr0551	gene:10499588	gene:10500377	ORF_ID:slr0376; unknown protein.	Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.	0.542
slr0376	slr0789	gene:10499588	gene:10500199	ORF_ID:slr0376; unknown protein.	ORF_ID:slr0789; unknown protein.	0.680
slr0541	slr0789	gene:10500339	gene:10500199	ORF_ID:slr0541; hypothetical protein.	ORF_ID:slr0789; unknown protein.	0.423
slr0551	guaA	gene:10500377	gene:10499709	Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	0.408
slr0551	slr0376	gene:10500377	gene:10499588	Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.	ORF_ID:slr0376; unknown protein.	0.542
slr0551	slr0789	gene:10500377	gene:10500199	Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.	ORF_ID:slr0789; unknown protein.	0.549
slr0789	cbbZp	gene:10500199	gene:10498431	ORF_ID:slr0789; unknown protein.	Phosphoglycolate phosphatase; ORF_ID:sll1349.	0.441
slr0789	guaA	gene:10500199	gene:10499709	ORF_ID:slr0789; unknown protein.	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	0.848
slr0789	slr0245	gene:10500199	gene:10497564	ORF_ID:slr0789; unknown protein.	Acetylpolyamine aminohydolase; Putative deacetylase.	0.526
slr0789	slr0376	gene:10500199	gene:10499588	ORF_ID:slr0789; unknown protein.	ORF_ID:slr0376; unknown protein.	0.680
slr0789	slr0541	gene:10500199	gene:10500339	ORF_ID:slr0789; unknown protein.	ORF_ID:slr0541; hypothetical protein.	0.423
slr0789	slr0551	gene:10500199	gene:10500377	ORF_ID:slr0789; unknown protein.	Ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.	0.549
slr0789	ssr2016	gene:10500199	gene:10498252	ORF_ID:slr0789; unknown protein.	ORF_ID:ssr2016; unknown protein.	0.549
slr0789	umuC	gene:10500199	gene:10500200	ORF_ID:slr0789; unknown protein.	UmuC protein; ORF_ID:slr0790.	0.741
ssr2016	slr0789	gene:10498252	gene:10500199	ORF_ID:ssr2016; unknown protein.	ORF_ID:slr0789; unknown protein.	0.549
umuC	slr0789	gene:10500200	gene:10500199	UmuC protein; ORF_ID:slr0790.	ORF_ID:slr0789; unknown protein.	0.741

Network Stats

number of nodes:

11

number of edges:

28

average node degree:

5.09

avg. local clustering coefficient:

0.773

expected number of edges:

11

PPI enrichment p-value:

2.66e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006730

One-carbon metabolic process

3 of 9

2.0

1.21

0.0053

GO:0006556

S-adenosylmethionine biosynthetic process

2 of 2

2.48

0.88

0.0278

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004478

Methionine adenosyltransferase activity

2 of 2

2.48

0.86

0.0307

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2229

Mixed, incl. Mismatch repair complex, and Protein of unknown function DUF2971

6 of 10

2.26

4.41

1.05e-09

CL:2232

Mixed, incl. Mismatch repair complex, and DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

5 of 5

2.48

4.22

1.00e-08

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

rbc00270

Cysteine and methionine metabolism

4 of 20

1.78

1.97

5.65e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0554

One-carbon metabolism

3 of 7

2.11

1.73

0.00054

KW-0630

Potassium

2 of 8

1.88

0.77

0.0384

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02773

S-adenosylmethionine synthetase, C-terminal domain

2 of 2

2.48

0.93

0.0228

PF02772

S-adenosylmethionine synthetase, central domain

2 of 2

2.48

0.93

0.0228

PF00438

S-adenosylmethionine synthetase, N-terminal domain

2 of 2

2.48

0.93

0.0228

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