STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 0.973
metH
Methionine synthase.
  
 
 0.938
mccB
Cystathionine gamma-lyase.
   
 0.887
tipA_2
HTH-type transcriptional activator tipA.
  
 
 0.861
metF
5%2C10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.835
aspC
Aspartate aminotransferase.
  
 0.834
CUN80125.1
Methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase.
    
 0.823
coaBC
DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 0.815
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
 
  
 0.815
CUN35075.1
Uncharacterised protein.
    
 0.808
Your Current Organism:
Fusicatenibacter saccharivorans
NCBI taxonomy Id: 1150298
Other names: Clostridium sp. HT03-11, Clostridium sp. HT03-14, Clostridium sp. HT03-186, Clostridium sp. HT03-22, Clostridium sp. KO-38, Clostridium sp. TT-111, DSM 26062, F. saccharivorans, Fusicatenibacter saccharivorans Takada et al. 2013, JCM 18507, YIT 12554, strain HT03-11
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