STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (455 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 0.998
SFW33472.1
Kynurenine formamidase.
 
  
 0.951
SFW66304.1
Amino acid adenylation domain-containing protein.
   
 0.826
SFW57491.1
Acetyl esterase/lipase.
   
 
 0.817
SFW50692.1
Ferredoxin.
     
 0.795
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.
 
     0.793
SFW41682.1
Tryptophan 2,3-dioxygenase apoenzyme.
 
 
 0.778
SFW72559.1
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
   
  
 0.639
SFW51996.1
Beta-carotene 3-hydroxylase.
   
 0.607
SFW46037.1
ABC-type nitrate/sulfonate/bicarbonate transport system, substrate-binding protein.
  
   
 0.591
Your Current Organism:
Sinomicrobium oceani
NCBI taxonomy Id: 1150368
Other names: CGMCC 1.12145, Flavobacteriaceae bacterium SCSIO 03483, KCTC 23994, S. oceani, SCSIO 03483, Sinomicrobium oceani Xu et al. 2013
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