STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFW75897.12-iminoacetate synthase. (387 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 0.999
thiE
Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase/thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.996
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.989
SFW75876.1
Thiamine-phosphate pyrophosphorylase.
 
  
 0.981
SFW75864.1
Sulfur carrier protein ThiS (thiamine biosynthesis).
  
 
 0.921
SFW38138.1
Glycine/D-amino acid oxidase.
    
  0.870
SFW75916.1
Adenylyltransferase and sulfurtransferase.
  
 0.812
SFW14059.1
HPt (histidine-containing phosphotransfer) domain-containing protein.
  
    0.677
SFW51324.1
Adenosylhomocysteine nucleosidase.
     
 0.506
SFW77289.1
Regulatory protein, luxR family.
  
  
 0.486
Your Current Organism:
Sinomicrobium oceani
NCBI taxonomy Id: 1150368
Other names: CGMCC 1.12145, Flavobacteriaceae bacterium SCSIO 03483, KCTC 23994, S. oceani, SCSIO 03483, Sinomicrobium oceani Xu et al. 2013
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.