node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCG06661.1 | CCG07150.1 | RSPPHO_00035 | RSPPHO_00524 | DNA repair protein RadC; Belongs to the UPF0758 family. | Maf-like protein Rru_A2768; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.748 |
CCG06661.1 | CCG08153.1 | RSPPHO_00035 | RSPPHO_01527 | DNA repair protein RadC; Belongs to the UPF0758 family. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.816 |
CCG06922.1 | CCG07150.1 | RSPPHO_00296 | RSPPHO_00524 | Malate dehydrogenase. | Maf-like protein Rru_A2768; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.460 |
CCG06922.1 | hisG | RSPPHO_00296 | RSPPHO_00519 | Malate dehydrogenase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.457 |
CCG06922.1 | purA | RSPPHO_00296 | RSPPHO_01872 | Malate dehydrogenase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.510 |
CCG07147.1 | CCG07148.1 | RSPPHO_00521 | RSPPHO_00522 | UPF0262 protein Rru_A2770; Belongs to the UPF0262 family. | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.988 |
CCG07147.1 | CCG07150.1 | RSPPHO_00521 | RSPPHO_00524 | UPF0262 protein Rru_A2770; Belongs to the UPF0262 family. | Maf-like protein Rru_A2768; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.588 |
CCG07147.1 | CCG07151.1 | RSPPHO_00521 | RSPPHO_00525 | UPF0262 protein Rru_A2770; Belongs to the UPF0262 family. | Ribonuclease G (RNase G). | 0.537 |
CCG07147.1 | hisD | RSPPHO_00521 | RSPPHO_00520 | UPF0262 protein Rru_A2770; Belongs to the UPF0262 family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.834 |
CCG07147.1 | hisG | RSPPHO_00521 | RSPPHO_00519 | UPF0262 protein Rru_A2770; Belongs to the UPF0262 family. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.834 |
CCG07147.1 | infA | RSPPHO_00521 | RSPPHO_00523 | UPF0262 protein Rru_A2770; Belongs to the UPF0262 family. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.591 |
CCG07148.1 | CCG07147.1 | RSPPHO_00522 | RSPPHO_00521 | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | UPF0262 protein Rru_A2770; Belongs to the UPF0262 family. | 0.988 |
CCG07148.1 | CCG07150.1 | RSPPHO_00522 | RSPPHO_00524 | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Maf-like protein Rru_A2768; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.588 |
CCG07148.1 | CCG07151.1 | RSPPHO_00522 | RSPPHO_00525 | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Ribonuclease G (RNase G). | 0.547 |
CCG07148.1 | hisD | RSPPHO_00522 | RSPPHO_00520 | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.834 |
CCG07148.1 | hisG | RSPPHO_00522 | RSPPHO_00519 | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.851 |
CCG07148.1 | infA | RSPPHO_00522 | RSPPHO_00523 | Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.632 |
CCG07150.1 | CCG06661.1 | RSPPHO_00524 | RSPPHO_00035 | Maf-like protein Rru_A2768; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | DNA repair protein RadC; Belongs to the UPF0758 family. | 0.748 |
CCG07150.1 | CCG06922.1 | RSPPHO_00524 | RSPPHO_00296 | Maf-like protein Rru_A2768; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Malate dehydrogenase. | 0.460 |
CCG07150.1 | CCG07147.1 | RSPPHO_00524 | RSPPHO_00521 | Maf-like protein Rru_A2768; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | UPF0262 protein Rru_A2770; Belongs to the UPF0262 family. | 0.588 |