CCG07478.1 protein (Pararhodospirillum photometricum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

CCG07478.1

Tetratricopeptide TPR_4. (183 aa)

Predicted Functional Partners:

CCG08898.1

0.742

CCG07090.1

0.723

CCG06734.1

0.722

CCG06741.1

0.711

CCG09722.1

0.698

CCG08251.1

0.685

lptD

0.673

CCG07622.1

0.661

CCG07446.1

0.659

CCG08014.1

0.649

Your Current Organism:

Pararhodospirillum photometricum

NCBI taxonomy Id: 1150469
Other names: P. photometricum DSM 122, Pararhodospirillum photometricum DSM 122, Rhodospirillum photometricum DSM 122

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCG06734.1	CCG06741.1	RSPPHO_00108	RSPPHO_00115	Putative uncharacterized protein.	Putative uncharacterized protein.	0.454
CCG06734.1	CCG07090.1	RSPPHO_00108	RSPPHO_00464	Putative uncharacterized protein.	Putative uncharacterized protein.	0.474
CCG06734.1	CCG07446.1	RSPPHO_00108	RSPPHO_00820	Putative uncharacterized protein.	Putative uncharacterized protein.	0.701
CCG06734.1	CCG07478.1	RSPPHO_00108	RSPPHO_00852	Putative uncharacterized protein.	Tetratricopeptide TPR_4.	0.722
CCG06734.1	CCG07622.1	RSPPHO_00108	RSPPHO_00996	Putative uncharacterized protein.	Response regulator receiver domain protein (CheY).	0.612
CCG06734.1	CCG08014.1	RSPPHO_00108	RSPPHO_01388	Putative uncharacterized protein.	Putative uncharacterized protein.	0.682
CCG06734.1	CCG08251.1	RSPPHO_00108	RSPPHO_01625	Putative uncharacterized protein.	Putative uncharacterized protein.	0.607
CCG06734.1	CCG08898.1	RSPPHO_00108	RSPPHO_02272	Putative uncharacterized protein.	Putative uncharacterized protein.	0.762
CCG06734.1	CCG09722.1	RSPPHO_00108	RSPPHO_03096	Putative uncharacterized protein.	Putative uncharacterized protein.	0.773
CCG06741.1	CCG06734.1	RSPPHO_00115	RSPPHO_00108	Putative uncharacterized protein.	Putative uncharacterized protein.	0.454
CCG06741.1	CCG07090.1	RSPPHO_00115	RSPPHO_00464	Putative uncharacterized protein.	Putative uncharacterized protein.	0.735
CCG06741.1	CCG07478.1	RSPPHO_00115	RSPPHO_00852	Putative uncharacterized protein.	Tetratricopeptide TPR_4.	0.711
CCG06741.1	CCG08898.1	RSPPHO_00115	RSPPHO_02272	Putative uncharacterized protein.	Putative uncharacterized protein.	0.495
CCG06741.1	lptD	RSPPHO_00115	RSPPHO_01107	Putative uncharacterized protein.	Organic solvent tolerance protein OstA-like; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.	0.613
CCG07090.1	CCG06734.1	RSPPHO_00464	RSPPHO_00108	Putative uncharacterized protein.	Putative uncharacterized protein.	0.474
CCG07090.1	CCG06741.1	RSPPHO_00464	RSPPHO_00115	Putative uncharacterized protein.	Putative uncharacterized protein.	0.735
CCG07090.1	CCG07478.1	RSPPHO_00464	RSPPHO_00852	Putative uncharacterized protein.	Tetratricopeptide TPR_4.	0.723
CCG07090.1	CCG07622.1	RSPPHO_00464	RSPPHO_00996	Putative uncharacterized protein.	Response regulator receiver domain protein (CheY).	0.671
CCG07090.1	CCG08898.1	RSPPHO_00464	RSPPHO_02272	Putative uncharacterized protein.	Putative uncharacterized protein.	0.635
CCG07090.1	CCG09722.1	RSPPHO_00464	RSPPHO_03096	Putative uncharacterized protein.	Putative uncharacterized protein.	0.431

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.903

expected number of edges:

10

PPI enrichment p-value:

0.000173

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006260

DNA replication

8 of 46

1.55

2.55

1.08e-08

GO:0006259

DNA metabolic process

9 of 117

1.19

1.57

1.10e-07

GO:0006261

DNA-templated DNA replication

3 of 16

1.58

1.09

0.0046

GO:0034654

Nucleobase-containing compound biosynthetic process

6 of 108

1.05

0.92

0.00065

GO:0006269

DNA replication, synthesis of RNA primer

2 of 5

1.91

0.87

0.0220

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003887

DNA-directed DNA polymerase activity

4 of 14

1.76

1.71

0.00019

GO:0016779

Nucleotidyltransferase activity

5 of 36

1.45

0.00019

GO:0140097

Catalytic activity, acting on DNA

6 of 66

1.26

1.25

0.00019

GO:0140640

Catalytic activity, acting on a nucleic acid

7 of 150

0.97

0.91

0.00019

GO:0003677

DNA binding

8 of 187

0.94

0.86

0.00019

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030894

Replisome

3 of 6

2.0

1.57

0.00080

GO:0061695

Transferase complex, transferring phosphorus-containing groups

3 of 9

1.83

1.5

0.00080

GO:0009360

DNA polymerase III complex

2 of 3

2.13

1.33

0.0030

GO:0140535

Intracellular protein-containing complex

3 of 15

1.61

1.28

0.0015

GO:1990077

Primosome complex

2 of 4

2.0

1.26

0.0036

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:575

DNA replication, and Bacterial nucleoid

8 of 14

2.06

5.07

5.57e-13

CL:523

Mismatch repair, and DNA damage

10 of 40

1.7

3.97

6.50e-14

CL:591

Primosome, and Bacterial nucleoid

4 of 6

2.13

2.61

5.39e-06

CL:579

DNA polymerase III subunits gamma and tau domain III, and Helix-hairpin-helix motif

3 of 5

2.08

1.77

0.00034

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03030

DNA replication

7 of 31

1.66

2.86

7.89e-09

map03430

Mismatch repair

6 of 27

1.65

2.54

1.54e-07

map03440

Homologous recombination

6 of 36

1.53

2.18

4.78e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009360

DNA polymerase III complex

3 of 4

2.18

1.87

0.00024

GOCC:0061695

Transferase complex, transferring phosphorus-containing groups

5 of 31

1.51

1.62

8.25e-05

GOCC:1990077

Primosome complex

2 of 6

1.83

0.87

0.0204

GOCC:1902494

Catalytic complex

6 of 130

0.97

0.83

0.00077

GOCC:0032991

Protein-containing complex

7 of 315

0.65

0.46

0.0093

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0235

DNA replication

6 of 15

1.91

3.25

2.46e-08

KW-0238

DNA-binding

7 of 105

1.13

1.24

1.61e-05

KW-0639

Primosome

2 of 2

2.31

1.14

0.0076

KW-0239

DNA-directed DNA polymerase

2 of 5

1.91

0.94

0.0159

KW-0548

Nucleotidyltransferase

3 of 22

1.44

0.93

0.0084

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR027417

P-loop containing nucleoside triphosphate hydrolase

7 of 152

0.97

0.78

0.0019

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