node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCG06882.1 | CCG08306.1 | RSPPHO_00256 | RSPPHO_01680 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Periplasmic protein thiol-disulfide oxidoreductase DsbE. | 0.465 |
CCG06882.1 | CCG08319.1 | RSPPHO_00256 | RSPPHO_01693 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | 0.457 |
CCG06882.1 | msrA | RSPPHO_00256 | RSPPHO_00872 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.621 |
CCG08102.1 | msrA | RSPPHO_01476 | RSPPHO_00872 | Glutaredoxin, GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.666 |
CCG08306.1 | CCG06882.1 | RSPPHO_01680 | RSPPHO_00256 | Periplasmic protein thiol-disulfide oxidoreductase DsbE. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.465 |
CCG08306.1 | CCG08319.1 | RSPPHO_01680 | RSPPHO_01693 | Periplasmic protein thiol-disulfide oxidoreductase DsbE. | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | 0.661 |
CCG08306.1 | CCG09823.1 | RSPPHO_01680 | RSPPHO_03197 | Periplasmic protein thiol-disulfide oxidoreductase DsbE. | Putative suppressor for copper-sensitivity B. | 0.951 |
CCG08306.1 | CCG09824.1 | RSPPHO_01680 | RSPPHO_03198 | Periplasmic protein thiol-disulfide oxidoreductase DsbE. | Putative suppressor for copper-sensitivity B. | 0.929 |
CCG08306.1 | msrA | RSPPHO_01680 | RSPPHO_00872 | Periplasmic protein thiol-disulfide oxidoreductase DsbE. | Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.926 |
CCG08306.1 | polA | RSPPHO_01680 | RSPPHO_02779 | Periplasmic protein thiol-disulfide oxidoreductase DsbE. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.456 |
CCG08319.1 | CCG06882.1 | RSPPHO_01693 | RSPPHO_00256 | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.457 |
CCG08319.1 | CCG08306.1 | RSPPHO_01693 | RSPPHO_01680 | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | Periplasmic protein thiol-disulfide oxidoreductase DsbE. | 0.661 |
CCG08319.1 | CCG08968.1 | RSPPHO_01693 | RSPPHO_02342 | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | Thiol-disulfide isomerase and thioredoxins. | 0.630 |
CCG08319.1 | CCG09823.1 | RSPPHO_01693 | RSPPHO_03197 | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | Putative suppressor for copper-sensitivity B. | 0.685 |
CCG08319.1 | CCG09824.1 | RSPPHO_01693 | RSPPHO_03198 | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | Putative suppressor for copper-sensitivity B. | 0.685 |
CCG08319.1 | msrA | RSPPHO_01693 | RSPPHO_00872 | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.995 |
CCG08319.1 | polA | RSPPHO_01693 | RSPPHO_02779 | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.557 |
CCG08968.1 | CCG08319.1 | RSPPHO_02342 | RSPPHO_01693 | Thiol-disulfide isomerase and thioredoxins. | Protein-methionine-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | 0.630 |
CCG08968.1 | CCG09823.1 | RSPPHO_02342 | RSPPHO_03197 | Thiol-disulfide isomerase and thioredoxins. | Putative suppressor for copper-sensitivity B. | 0.752 |
CCG08968.1 | CCG09824.1 | RSPPHO_02342 | RSPPHO_03198 | Thiol-disulfide isomerase and thioredoxins. | Putative suppressor for copper-sensitivity B. | 0.739 |