node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCG07453.1 | CCG08049.1 | RSPPHO_00827 | RSPPHO_01423 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.558 |
CCG07453.1 | CCG08205.1 | RSPPHO_00827 | RSPPHO_01579 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Regulatory inactivation of DnaA Hda protein. | 0.986 |
CCG07453.1 | recF | RSPPHO_00827 | RSPPHO_00828 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.896 |
CCG07453.1 | recF-2 | RSPPHO_00827 | RSPPHO_00829 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.889 |
CCG07453.1 | recO | RSPPHO_00827 | RSPPHO_00732 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.636 |
CCG07453.1 | rnpA | RSPPHO_00827 | RSPPHO_01808 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease P protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.640 |
CCG08049.1 | CCG07453.1 | RSPPHO_01423 | RSPPHO_00827 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.558 |
CCG08049.1 | CCG08205.1 | RSPPHO_01423 | RSPPHO_01579 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Regulatory inactivation of DnaA Hda protein. | 0.644 |
CCG08049.1 | recO | RSPPHO_01423 | RSPPHO_00732 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.402 |
CCG08205.1 | CCG07453.1 | RSPPHO_01579 | RSPPHO_00827 | Regulatory inactivation of DnaA Hda protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.986 |
CCG08205.1 | CCG08049.1 | RSPPHO_01579 | RSPPHO_01423 | Regulatory inactivation of DnaA Hda protein. | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.644 |
CCG08205.1 | CCG08206.1 | RSPPHO_01579 | RSPPHO_01580 | Regulatory inactivation of DnaA Hda protein. | Putative uncharacterized protein. | 0.981 |
CCG08205.1 | CCG08207.1 | RSPPHO_01579 | RSPPHO_01581 | Regulatory inactivation of DnaA Hda protein. | Enoyl-CoA hydratase / short chain enoyl-CoA hydratase. | 0.773 |
CCG08205.1 | recF | RSPPHO_01579 | RSPPHO_00828 | Regulatory inactivation of DnaA Hda protein. | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.652 |
CCG08205.1 | recF-2 | RSPPHO_01579 | RSPPHO_00829 | Regulatory inactivation of DnaA Hda protein. | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.654 |
CCG08205.1 | recO | RSPPHO_01579 | RSPPHO_00732 | Regulatory inactivation of DnaA Hda protein. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.595 |
CCG08205.1 | rnpA | RSPPHO_01579 | RSPPHO_01808 | Regulatory inactivation of DnaA Hda protein. | Ribonuclease P protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.626 |
CCG08205.1 | rpmE | RSPPHO_01579 | RSPPHO_00930 | Regulatory inactivation of DnaA Hda protein. | 50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.728 |
CCG08205.1 | rpmJ | RSPPHO_01579 | RSPPHO_01937 | Regulatory inactivation of DnaA Hda protein. | 50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. | 0.620 |
CCG08206.1 | CCG08205.1 | RSPPHO_01580 | RSPPHO_01579 | Putative uncharacterized protein. | Regulatory inactivation of DnaA Hda protein. | 0.981 |