node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCG07542.1 | CCG08439.1 | RSPPHO_00916 | RSPPHO_01813 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyrimidine 5-nucleotidase. | 0.554 |
CCG07542.1 | argB | RSPPHO_00916 | RSPPHO_01812 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.424 |
CCG07542.1 | guaB | RSPPHO_00916 | RSPPHO_01069 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.798 |
CCG07542.1 | nadE | RSPPHO_00916 | RSPPHO_00651 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.771 |
CCG07542.1 | polA | RSPPHO_00916 | RSPPHO_02779 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.659 |
CCG07542.1 | ribB | RSPPHO_00916 | RSPPHO_00914 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
CCG07542.1 | rnpA | RSPPHO_00916 | RSPPHO_01808 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ribonuclease P protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.514 |
CCG08435.1 | CCG08439.1 | RSPPHO_01809 | RSPPHO_01813 | UPF0161 protein Rru_A3338; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Pyrimidine 5-nucleotidase. | 0.451 |
CCG08435.1 | argB | RSPPHO_01809 | RSPPHO_01812 | UPF0161 protein Rru_A3338; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.660 |
CCG08435.1 | engB | RSPPHO_01809 | RSPPHO_01811 | UPF0161 protein Rru_A3338; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Probable GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.765 |
CCG08435.1 | rnpA | RSPPHO_01809 | RSPPHO_01808 | UPF0161 protein Rru_A3338; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Ribonuclease P protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.990 |
CCG08435.1 | yidC | RSPPHO_01809 | RSPPHO_01810 | UPF0161 protein Rru_A3338; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.949 |
CCG08439.1 | CCG07542.1 | RSPPHO_01813 | RSPPHO_00916 | Pyrimidine 5-nucleotidase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.554 |
CCG08439.1 | CCG08435.1 | RSPPHO_01813 | RSPPHO_01809 | Pyrimidine 5-nucleotidase. | UPF0161 protein Rru_A3338; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.451 |
CCG08439.1 | argB | RSPPHO_01813 | RSPPHO_01812 | Pyrimidine 5-nucleotidase. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.585 |
CCG08439.1 | engB | RSPPHO_01813 | RSPPHO_01811 | Pyrimidine 5-nucleotidase. | Probable GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.536 |
CCG08439.1 | guaB | RSPPHO_01813 | RSPPHO_01069 | Pyrimidine 5-nucleotidase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.554 |
CCG08439.1 | nadE | RSPPHO_01813 | RSPPHO_00651 | Pyrimidine 5-nucleotidase. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.579 |
CCG08439.1 | polA | RSPPHO_01813 | RSPPHO_02779 | Pyrimidine 5-nucleotidase. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.469 |
CCG08439.1 | ribB | RSPPHO_01813 | RSPPHO_00914 | Pyrimidine 5-nucleotidase. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.476 |