node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCG06880.1 | CCG06882.1 | RSPPHO_00254 | RSPPHO_00256 | Transcriptional regulator, ArsR family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.834 |
CCG06880.1 | CCG07542.1 | RSPPHO_00254 | RSPPHO_00916 | Transcriptional regulator, ArsR family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.514 |
CCG06880.1 | CCG08589.1 | RSPPHO_00254 | RSPPHO_01963 | Transcriptional regulator, ArsR family. | Membrane anion transport protein. | 0.552 |
CCG06880.1 | nifJ | RSPPHO_00254 | RSPPHO_02736 | Transcriptional regulator, ArsR family. | Pyruvate-flavodoxin oxidoreductase. | 0.663 |
CCG06882.1 | CCG06880.1 | RSPPHO_00256 | RSPPHO_00254 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Transcriptional regulator, ArsR family. | 0.834 |
CCG06882.1 | CCG07542.1 | RSPPHO_00256 | RSPPHO_00916 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.414 |
CCG06882.1 | CCG08589.1 | RSPPHO_00256 | RSPPHO_01963 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Membrane anion transport protein. | 0.403 |
CCG06882.1 | guaA | RSPPHO_00256 | RSPPHO_00491 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.604 |
CCG06882.1 | nifJ | RSPPHO_00256 | RSPPHO_02736 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate-flavodoxin oxidoreductase. | 0.643 |
CCG07542.1 | CCG06880.1 | RSPPHO_00916 | RSPPHO_00254 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Transcriptional regulator, ArsR family. | 0.514 |
CCG07542.1 | CCG06882.1 | RSPPHO_00916 | RSPPHO_00256 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.414 |
CCG07542.1 | CCG08589.1 | RSPPHO_00916 | RSPPHO_01963 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Membrane anion transport protein. | 0.408 |
CCG07542.1 | guaA | RSPPHO_00916 | RSPPHO_00491 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.634 |
CCG07542.1 | polA | RSPPHO_00916 | RSPPHO_02779 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.659 |
CCG08589.1 | CCG06880.1 | RSPPHO_01963 | RSPPHO_00254 | Membrane anion transport protein. | Transcriptional regulator, ArsR family. | 0.552 |
CCG08589.1 | CCG06882.1 | RSPPHO_01963 | RSPPHO_00256 | Membrane anion transport protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.403 |
CCG08589.1 | CCG07542.1 | RSPPHO_01963 | RSPPHO_00916 | Membrane anion transport protein. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.408 |
CCG08589.1 | CCG08590.1 | RSPPHO_01963 | RSPPHO_01964 | Membrane anion transport protein. | Transposase (Class II). | 0.470 |
CCG08589.1 | guaA | RSPPHO_01963 | RSPPHO_00491 | Membrane anion transport protein. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.538 |
CCG08589.1 | nifJ | RSPPHO_01963 | RSPPHO_02736 | Membrane anion transport protein. | Pyruvate-flavodoxin oxidoreductase. | 0.440 |