node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCG06758.1 | CCG06882.1 | RSPPHO_00132 | RSPPHO_00256 | Cystathionine beta-lyase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.976 |
CCG06758.1 | CCG07492.1 | RSPPHO_00132 | RSPPHO_00866 | Cystathionine beta-lyase. | Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.923 |
CCG06758.1 | CCG08657.1 | RSPPHO_00132 | RSPPHO_02031 | Cystathionine beta-lyase. | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.937 |
CCG06758.1 | CCG09035.1 | RSPPHO_00132 | RSPPHO_02409 | Cystathionine beta-lyase. | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.936 |
CCG06758.1 | CCG09455.1 | RSPPHO_00132 | RSPPHO_02829 | Cystathionine beta-lyase. | Cysteine synthase. | 0.988 |
CCG06758.1 | ahcY | RSPPHO_00132 | RSPPHO_02739 | Cystathionine beta-lyase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.921 |
CCG06758.1 | metAA | RSPPHO_00132 | RSPPHO_03163 | Cystathionine beta-lyase. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.513 |
CCG06758.1 | metC | RSPPHO_00132 | RSPPHO_01995 | Cystathionine beta-lyase. | Cystathionine beta-lyase. | 0.907 |
CCG06758.1 | metZ | RSPPHO_00132 | RSPPHO_00479 | Cystathionine beta-lyase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.923 |
CCG06882.1 | CCG06758.1 | RSPPHO_00256 | RSPPHO_00132 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase. | 0.976 |
CCG06882.1 | CCG07492.1 | RSPPHO_00256 | RSPPHO_00866 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.976 |
CCG06882.1 | CCG08657.1 | RSPPHO_00256 | RSPPHO_02031 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.954 |
CCG06882.1 | CCG09035.1 | RSPPHO_00256 | RSPPHO_02409 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.963 |
CCG06882.1 | CCG09455.1 | RSPPHO_00256 | RSPPHO_02829 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase. | 0.953 |
CCG06882.1 | ahcY | RSPPHO_00256 | RSPPHO_02739 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.966 |
CCG06882.1 | metAA | RSPPHO_00256 | RSPPHO_03163 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.902 |
CCG06882.1 | metC | RSPPHO_00256 | RSPPHO_01995 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase. | 0.976 |
CCG06882.1 | metX | RSPPHO_00256 | RSPPHO_01415 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.836 |
CCG06882.1 | metZ | RSPPHO_00256 | RSPPHO_00479 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.976 |
CCG07492.1 | CCG06758.1 | RSPPHO_00866 | RSPPHO_00132 | Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | Cystathionine beta-lyase. | 0.923 |