STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCG08747.12-oxoglutarate dehydrogenase E2 component. (127 aa)    
Predicted Functional Partners:
CCG06838.1
Pyruvate dehydrogenase beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.997
CCG08514.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.997
CCG08748.1
2-oxoglutarate dehydrogenase E2 component.
     0.989
pdhA
Pyruvate dehydrogenase (Lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.981
CCG08749.1
Dihydrolipoamide dehydrogenase.
 
 0.978
CCG08776.1
Dihydrolipoyl dehydrogenase.
 
 0.954
CCG07267.1
NADPH-glutathione reductase; Maintains high levels of reduced glutathione.
 
 0.919
CCG07207.1
NAD-reducing hydrogenase diaphorase moiety largesubunit.
   
 
 0.897
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.871
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.864
Your Current Organism:
Pararhodospirillum photometricum
NCBI taxonomy Id: 1150469
Other names: P. photometricum DSM 122, Pararhodospirillum photometricum DSM 122, Rhodospirillum photometricum DSM 122
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