node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCG07931.1 | CCG08049.1 | RSPPHO_01305 | RSPPHO_01423 | DNA polymerase III, delta prime subunit. | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.653 |
CCG07931.1 | CCG08544.1 | RSPPHO_01305 | RSPPHO_01918 | DNA polymerase III, delta prime subunit. | DNA polymerase III, chi subunit. | 0.892 |
CCG07931.1 | CCG09584.1 | RSPPHO_01305 | RSPPHO_02958 | DNA polymerase III, delta prime subunit. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.900 |
CCG07931.1 | CCG09775.1 | RSPPHO_01305 | RSPPHO_03149 | DNA polymerase III, delta prime subunit. | DNA polymerase III, alpha subunit. | 0.710 |
CCG07931.1 | CCG09776.1 | RSPPHO_01305 | RSPPHO_03150 | DNA polymerase III, delta prime subunit. | DNA polymerase III, alpha subunit. | 0.710 |
CCG07931.1 | topA | RSPPHO_01305 | RSPPHO_01138 | DNA polymerase III, delta prime subunit. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.442 |
CCG08049.1 | CCG07931.1 | RSPPHO_01423 | RSPPHO_01305 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, delta prime subunit. | 0.653 |
CCG08049.1 | CCG08091.1 | RSPPHO_01423 | RSPPHO_01465 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Primosomal protein n. | 0.506 |
CCG08049.1 | CCG09584.1 | RSPPHO_01423 | RSPPHO_02958 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.884 |
CCG08049.1 | CCG09775.1 | RSPPHO_01423 | RSPPHO_03149 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, alpha subunit. | 0.622 |
CCG08049.1 | CCG09776.1 | RSPPHO_01423 | RSPPHO_03150 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, alpha subunit. | 0.654 |
CCG08049.1 | dnaX | RSPPHO_01423 | RSPPHO_01471 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA-directed DNA polymerase; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.694 |
CCG08049.1 | topA | RSPPHO_01423 | RSPPHO_01138 | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.635 |
CCG08091.1 | CCG08049.1 | RSPPHO_01465 | RSPPHO_01423 | Primosomal protein n. | DnaB helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.506 |
CCG08091.1 | CCG09584.1 | RSPPHO_01465 | RSPPHO_02958 | Primosomal protein n. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.916 |
CCG08544.1 | CCG07931.1 | RSPPHO_01918 | RSPPHO_01305 | DNA polymerase III, chi subunit. | DNA polymerase III, delta prime subunit. | 0.892 |
CCG08544.1 | CCG09584.1 | RSPPHO_01918 | RSPPHO_02958 | DNA polymerase III, chi subunit. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.893 |
CCG08544.1 | CCG09775.1 | RSPPHO_01918 | RSPPHO_03149 | DNA polymerase III, chi subunit. | DNA polymerase III, alpha subunit. | 0.893 |
CCG08544.1 | CCG09776.1 | RSPPHO_01918 | RSPPHO_03150 | DNA polymerase III, chi subunit. | DNA polymerase III, alpha subunit. | 0.893 |
CCG08544.1 | dnaX | RSPPHO_01918 | RSPPHO_01471 | DNA polymerase III, chi subunit. | DNA-directed DNA polymerase; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.892 |