STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupHHydrogenase expression/formation protein hupH; Function of homologous gene experimentally demonstrated in an other organism; phenotype. (268 aa)    
Predicted Functional Partners:
hupC
Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.
 
  
 0.994
hupS
Uptake hydrogenase small subunit (Hydrogenlyase) (Membrane-bound hydrogenase small subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.987
hupD
Hydrogenase maturation protein hupD; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.980
CCG39672.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
  
 0.978
hupJ
Hydrogenase expression/formation protein hupJ; Function of strongly homologous gene; phenotype.
 
  
 0.968
hupL
Uptake hydrogenase large subunit precursor; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.966
hupF
Hydrogenase expression/formation protein HupF; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.959
alkT
Rubredoxin-NAD(+) reductase.
  
 0.939
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.933
hypA
Hydrogenase expression/formation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.903
Your Current Organism:
Phaeospirillum molischianum
NCBI taxonomy Id: 1150626
Other names: P. molischianum DSM 120, Phaeospirillum molischianum DSM 120, Phaeospirillum molischianum str. DSM 120, Phaeospirillum molischianum strain DSM 120
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