STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypDHydrogenase expression/formation protein; Function of homologous gene experimentally demonstrated in an other organism; phenotype; Belongs to the HypD family. (384 aa)    
Predicted Functional Partners:
hypC
Hydrogenase expression/formation protein HypC; Function of homologous gene experimentally demonstrated in an other organism; phenotype.
 
 
 0.999
hypE
Hydrogenase maturation protein HypE; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
 0.999
hypB
Hydrogenase nickel incorporation protein hypB.
 
  
 0.993
hupF
Hydrogenase expression/formation protein HupF; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.989
hypF
Carbamoyl phosphate phosphatase, (NiFe) Hydrogenase maturation protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
  
 0.980
hypA
Hydrogenase expression/formation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.972
CCG39672.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.879
hupD
Hydrogenase maturation protein hupD; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.851
hupL
Uptake hydrogenase large subunit precursor; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.844
hupH
Hydrogenase expression/formation protein hupH; Function of homologous gene experimentally demonstrated in an other organism; phenotype.
  
  
 0.818
Your Current Organism:
Phaeospirillum molischianum
NCBI taxonomy Id: 1150626
Other names: P. molischianum DSM 120, Phaeospirillum molischianum DSM 120, Phaeospirillum molischianum str. DSM 120, Phaeospirillum molischianum strain DSM 120
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