STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ruvCCrossover junction endodeoxyribonuclease ruvC (Holliday junction nuclease ruvC); Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (166 aa)    
Predicted Functional Partners:
ruvA
Holliday junction DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
 0.999
ruvB
Holliday junction DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
 
 0.987
tolB
Protein tolB precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
     
 0.845
CCG40046.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
  
 0.838
ybgC
Thioesterase superfamily:4-hydroxybenzoyl-CoA thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.832
tolA
Periplasmic protein TolA, links inner and outer membranes; Function of homologous gene experimentally demonstrated in an other organism; membrane component.
       0.827
tolQ
TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
     
 0.813
tolR
Biopolymer transport TolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
       0.807
polA
DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.605
CCG41680.1
Putative single-stranded-DNA-specific exonuclease recJ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 
 0.600
Your Current Organism:
Phaeospirillum molischianum
NCBI taxonomy Id: 1150626
Other names: P. molischianum DSM 120, Phaeospirillum molischianum DSM 120, Phaeospirillum molischianum str. DSM 120, Phaeospirillum molischianum strain DSM 120
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