STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutYAdenine glycosylase mutY; Adenine glycosylase active on G-A mispairs. (364 aa)    
Predicted Functional Partners:
CCG40827.1
Putative exodeoxyribonuclease III (xthA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.888
CCG40934.1
Exodeoxyribonuclease III (Exonuclease III) (EXO III) (AP endonuclease VI) (fragment).
    
 0.888
CCG40935.1
Exodeoxyribonuclease III (fragment).
    
 0.888
dnaN
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.823
mutM
Bifunctional mutM protein:Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase); Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.788
dnaE
DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.755
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 
0.753
CCG42947.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.737
CCG42945.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.680
CCG41280.1
NTP pyrophosphohydrolase.
  
 
 0.547
Your Current Organism:
Phaeospirillum molischianum
NCBI taxonomy Id: 1150626
Other names: P. molischianum DSM 120, Phaeospirillum molischianum DSM 120, Phaeospirillum molischianum str. DSM 120, Phaeospirillum molischianum strain DSM 120
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