STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFJ09106.1Succinate dehydrogenase / fumarate reductase membrane anchor subunit. (137 aa)    
Predicted Functional Partners:
SFJ09072.1
Succinate dehydrogenase / fumarate reductase cytochrome b subunit.
 
 0.999
SFJ09135.1
Succinate dehydrogenase subunit A.
 
 0.999
SFJ09154.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
 
 0.999
SFK36682.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
  
 0.998
SFK36662.1
Succinate dehydrogenase / fumarate reductase flavoprotein subunit.
  
 0.997
SFK02773.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.985
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.982
SFK96365.1
2-oxoglutarate decarboxylase.
  
  
 0.972
SFK01826.1
3-oxosteroid 1-dehydrogenase.
  
 0.954
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.922
Your Current Organism:
Amycolatopsis sacchari
NCBI taxonomy Id: 115433
Other names: A. sacchari, Amycolatopsis sacchari Goodfellow et al. 2001, CIP 107029, DSM 44468, JCM 11272, KCTC 9863, NBRC 100339
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