STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFJ96483.1Methylenetetrahydrofolate reductase (NADPH); Belongs to the methylenetetrahydrofolate reductase family. (291 aa)    
Predicted Functional Partners:
SFI58425.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.990
SFJ96497.1
Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.
 
 
 0.940
folD-2
Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.912
SFJ96548.1
vanillate/3-O-methylgallate O-demethylase; Belongs to the GcvT family.
 
 
 0.888
SFK56263.1
Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.
 
 
 0.845
SFJ96364.1
Alpha/beta hydrolase family protein.
 
     0.840
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
    
 0.833
SFJ96407.1
Protocatechuate 4,5-dioxygenase, alpha chain.
 
     0.825
SFJ77145.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
 
 0.803
SFJ96387.1
Protocatechuate 4,5-dioxygenase, beta chain.
 
     0.803
Your Current Organism:
Amycolatopsis sacchari
NCBI taxonomy Id: 115433
Other names: A. sacchari, Amycolatopsis sacchari Goodfellow et al. 2001, CIP 107029, DSM 44468, JCM 11272, KCTC 9863, NBRC 100339
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