STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFJ95684.1Nitrogen regulatory protein P-II 1; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
SFK45031.1
Ammonium transporter, Amt family.
 
 0.998
glnD
[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
 
 0.980
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 
 0.948
SFI65086.1
ADP-ribosylglycohydrolase.
   
 
 0.785
SFK12231.1
Hypothetical protein.
   
 
 0.785
SFI94070.1
Glutamate synthase (NADPH/NADH) large chain.
 
  
 0.748
SFJ74339.1
Tetratricopeptide repeat-containing protein.
    
 
 0.731
SFJ97826.1
Tetratricopeptide repeat-containing protein.
    
 
 0.731
SFI75694.1
Tetratricopeptide repeat-containing protein.
    
 
 0.728
SFI90418.1
TIR domain-containing protein.
    
 
 0.728
Your Current Organism:
Amycolatopsis sacchari
NCBI taxonomy Id: 115433
Other names: A. sacchari, Amycolatopsis sacchari Goodfellow et al. 2001, CIP 107029, DSM 44468, JCM 11272, KCTC 9863, NBRC 100339
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.